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We appreciate the authors’ valuable contribution to providing a deeper understanding of the effectiveness of home-based oxygen therapy with bilevel positive airway pressure (Bi PAP) and that of osteopathic manipulative respiratory and physical therapy techniques in impeding exacerbation of early-stage COVID-19 pneumonia. However, the study should be further discussed in terms of research design, patient recruitment technologies, and the influence of the telemanagement system on health care development.
J Med Internet Res 2022;24(5):e34437
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Current evidence suggests that the application of noninvasive bilevel positive airway pressure (Bi PAP) can reduce pulmonary complications and raise pulmonary oxygen pressure by activation of collapsing alveoli and reduction of the degree of shunt [15].
J Med Internet Res 2021;23(4):e23446
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