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A clinical trial by Egan et al [7], which recruited participants through self-referral and included an assessment at 6 months following treatment, indicated that CBT, administered face-to-face or via the internet without any guidance, had within-group Cohen d effect sizes of 2.11 (face-to-face; 95% CI 1.26-2.88) and 0.43 (unguided self-help; 95% CI –0.28 to 1.12) on the FMPS CM. For the CPQ, Cohen d effect sizes were 1.61 (face-to-face; 95% CI 0.83-2.32) and 0.73 (unguided self-help; 95% CI –0.01 to 1.42).
J Med Internet Res 2018;20(4):e154
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A meta-analysis of randomized controlled trials (RCTs) of computer-based interventions for depression found that studies which included therapist support, or support from nonclinically trained guides, had medium effect sizes (d=0.78 and d=0.58, respectively), while the effect size for interventions without support was small (d=0.36) [25].
JMIR Res Protoc 2016;5(4):e215
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