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Improving Early Dementia Detection Among Diverse Older Adults With Cognitive Concerns With the 5-Cog Paradigm: Protocol for a Hybrid Effectiveness-Implementation Clinical Trial

Improving Early Dementia Detection Among Diverse Older Adults With Cognitive Concerns With the 5-Cog Paradigm: Protocol for a Hybrid Effectiveness-Implementation Clinical Trial

(D) IUH: negative 5-Cog result. At both sites, a paper token (Figure 4) is used as an additional feature to help ensure that care providers review the patients’ 5-Cog results. Patients are handed this token after they complete the 5-Cog battery and are asked to hand it to their care provider at their scheduled visit, generally within 30 minutes after the 5-Cog battery administration. Token to alert care provider for patient's 5-Cog participation.

Rachel Beth Rosansky Chalmer, Emmeline Ayers, Erica F Weiss, Nicole R Fowler, Andrew Telzak, Diana Summanwar, Jessica Zwerling, Cuiling Wang, Huiping Xu, Richard J Holden, Kevin Fiori, Dustin D French, Celeste Nsubayi, Asif Ansari, Paul Dexter, Anna Higbie, Pratibha Yadav, James M Walker, Harrshavasan Congivaram, Dristi Adhikari, Mairim Melecio-Vazquez, Malaz Boustani, Joe Verghese

JMIR Res Protoc 2025;14:e60471

Outcomes of a Remotely Delivered Complementary and Integrative Health Partnered Intervention to Improve Chronic Pain and Posttraumatic Stress Disorder Symptoms: Randomized Controlled Trial

Outcomes of a Remotely Delivered Complementary and Integrative Health Partnered Intervention to Improve Chronic Pain and Posttraumatic Stress Disorder Symptoms: Randomized Controlled Trial

The number of dyads was selected based on having adequate statistical power on the pain outcome measure to detect a small to medium effect size (Cohen d=0.38) given an anticipated 20% attrition rate. However, the observed attrition rate was roughly 33%, and the number of dyads recruited increased from the original target of 228 to a total of 364 dyads [88]. Participants in the qualitative inquiry comprised a subsample of 35 dyads that were recruited from the intervention arm of the parent MR study.

Jolie N Haun, Christopher A Fowler, Hari H Venkatachalam, Amy C Alman, Lisa M Ballistrea, Tali Schneider, Rachel C Benzinger, Christine Melillo, Neil B Alexander, S Angel Klanchar, William A Lapcevic, Matthew J Bair, Stephanie L Taylor, Jennifer L Murphy, Dustin D French

J Med Internet Res 2024;26:e57322

Mobile and Web-Based Partnered Intervention to Improve Remote Access to Pain and Posttraumatic Stress Disorder Symptom Management: Recruitment and Attrition in a Randomized Controlled Trial

Mobile and Web-Based Partnered Intervention to Improve Remote Access to Pain and Posttraumatic Stress Disorder Symptom Management: Recruitment and Attrition in a Randomized Controlled Trial

Assuming a within-participant correlation of 0.50 for PROs and a type I error rate of 0.05, recruitment of 228 dyads (76 per site) was expected to provide 80% power to detect a small-to-medium effect size (Cohen d=0.38) [27]. Protocol modifications for recruitment were made contemporaneously when the attrition rate exceeded expectations. Ultimately, 364 dyads consented to enroll in this study.

Jolie N Haun, Hari H Venkatachalam, Christopher A Fowler, Amy C Alman, Lisa M Ballistrea, Tali Schneider, Rachel C Benzinger, Christine Melillo, Neil B Alexander, S Angelina Klanchar, William Lapcevic, Dustin D French

J Med Internet Res 2023;25:e49678