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Skip search results from other journals and go to results- 4 JMIR Research Protocols
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Resveratrol, a naturally occurring food supplement available from nutraceutical companies, affects energy metabolism and mitochondrial function and has a short half-life in blood. This may explain the lack of consistent clinical efficacy in a range of mammalian and human conditions [5]. In contrast, bezafibrate is well established as a lipid-lowering agent in adults and children with a good safety record for long-term use [6].
JMIR Res Protoc 2021;10(5):e22533
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Currently, most RBC transfusions are given solely as a response to a hematocrit that has fallen below an arbitrary threshold and not as a response to incipient tissue hypoxia [15-17]. However, the hematocrit is a poor indicator of regional tissue hypoxia, and therefore is inadequate as an indicator of the need for transfusion.
The hematocrit below which oxygen delivery to tissues is reduced such that anaerobic metabolism occurs is known as the “critical hematocrit (Hct).”
JMIR Res Protoc 2015;4(4):e137
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Eligible next-of-kin and/or patients will be given a patient information leaflet (PIL), have the study explained to them, and will be given the opportunity to ask questions about the study. They will be given a minimum of 24 hours to consider the study prior to being asked to provide written informed consent if they are willing to participate in the study.
Participants will be randomly assigned in a 1:1 ratio to either the hypothermic group or the normothermic group.
JMIR Res Protoc 2015;4(2):e59
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We wish to test the specific hypothesis that propofol supplementation is cardioprotective and a recognized mechanism is postulated. For these reasons, intralipid has been chosen as the placebo for this trial.
Propofol is diluted in a 1:5 ratio with 0.9% sodium chloride as recommended by the manufacturer to achieve a working solution of 2000 μg/m L. Intralipid is diluted in the same manner.
JMIR Res Protoc 2014;3(3):e35
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