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In this paper, we describe our process for developing a direct recruitment protocol for use in gay dating apps that we implemented for a cooperative program project called Comprehensive Adolescent Research and Engagement Studies (CARES), which is one of 3 program projects and a coordinating center that comprises the Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN; Clinical Trials.gov NCT03134833) [18].
JMIR Res Protoc 2021;10(6):e28864
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Members of this study team rated the manuals of 5 of the CDC’s most popular, behaviorally oriented primary prevention EBIs for adolescents [36,40,41,42], finding that each of them incorporated common processes, principles, and factors.
JMIR Res Protoc 2019;8(8):e11165
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Each study and the overall design were approved by review boards of the Adolescent Medicine Trials Network (ATN) and the University of California, LA (IRB#16-001372).
CARES brings together an interdisciplinary team to design, implement, and evaluate every aspect of the 3 studies.
JMIR Res Protoc 2019;8(1):e10759
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To further demonstrate the effectiveness of early antiretroviral therapy on infants, a large multicenter phase 3 trial, National Institute of Child Health and Development HIV Prevention Trials Network 040, conducted by our team of investigators revealed that c ART reduced intrapartum HIV transmission by 50% [19] in high-risk HIV-exposed infants whose mothers did not receive c ART during pregnancy.
JMIR Res Protoc 2019;8(1):e10807
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The EDC system for ATN CARES incorporates multiple functions summarized above: data collection, mobile phone-based intervention delivery, and real-time data access for timely data quality monitoring and decision making that pertains to participant care. Most mobile EDC systems utilized in the past did not have multiple functions [21]. The ATN CARES population also provides opportunities to highlight the benefits and limitations of current mobile EDC systems.
JMIR Res Protoc 2018;7(12):e10777
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