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Approach to Design and Evaluate Digital Tools to Enhance Young Adult Participation in Clinical Trials: Co-Design and Controlled Intercept Study

Approach to Design and Evaluate Digital Tools to Enhance Young Adult Participation in Clinical Trials: Co-Design and Controlled Intercept Study

COVID-19 vaccine–related keywords “COVID-19 vaccine”, “COVID 19 vaccine”, “SARS-Co V2 vaccine”, “Coronavirus disease 2019 vaccine”, “m RNA-1273”, “Pfizer; Bio NTech”, “BNT162”, “Moderna”, “J&J” “Johnson & Johnson” Clinical trial–related keywords “Clinical trial”, “trial” Adapted inductive content coding approach of objective and subjective factors for clinical trial participation used in social listening analysis on Quora.

Tim Mackey, Raphael E Cuomo, Qing Xu, Tiana J McMann, Zhuoran Li, Mingxiang Cai, Christine Wenzel, Joshua S Yang

J Med Internet Res 2025;27:e70852

Safety and Efficacy of Modular Digital Psychotherapy for Social Anxiety: Randomized Controlled Trial

Safety and Efficacy of Modular Digital Psychotherapy for Social Anxiety: Randomized Controlled Trial

All analyses were conducted using Python (version 3.8.9; Python Software Foundation) and R (version 4.4.0; R Foundation for Statistical Computing). Eligible participants from the screening studies (158/350, 45.1% in RCT 1 and 349/1282, 27.22% in RCT 2; Figure 2) were invited to take part in the main study. RCT 1 included a total of 102 participants (all female aged between 18 and 35 years; n=52, 51% in the intervention group and n=50, 49% in the control group; Figure 2 A).

Mona M Garvert, Jessica McFadyen, Stuart Linke, Tayla McCloud, Sofie S Meyer, Sandra Sobanska, Paul B Sharp, Alex Long, Quentin J M Huys, Mandana Ahmadi

J Med Internet Res 2025;27:e64138