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Cooperative Virtual Reality Gaming for Anxiety and Pain Reduction in Pediatric Patients and Their Caregivers During Painful Medical Procedures: Protocol for a Randomized Controlled Trial

Cooperative Virtual Reality Gaming for Anxiety and Pain Reduction in Pediatric Patients and Their Caregivers During Painful Medical Procedures: Protocol for a Randomized Controlled Trial

On the basis of a power analysis with the G*Power software [22] and starting from a 2-sided t test with a significance level of α=.05 and a test power of 80%, we determined that a medium-size effect of approximately Cohen d=0.64 can be achieved with a corresponding sample size of 39 participants per group.

Stefan Liszio, Franziska Bäuerlein, Jens Hildebrand, Carolin van Nahl, Maic Masuch, Oliver Basu

JMIR Res Protoc 2025;14:e63098