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Social Media Activities With Different Content Characteristics and Adolescent Mental Health: Cross-Sectional Survey Study

Social Media Activities With Different Content Characteristics and Adolescent Mental Health: Cross-Sectional Survey Study

Unfortunately, if teenagers receive negative comments, those remarks linger in their thoughts for a long time, and lack of affirming feedback can also cause negative emotions [17]. The persistent thoughts of criticism and negative emotions may fuel future approval anxiety. Positive broadcasting highlights teenagers’ uplifting experiences, achievements, and friendships. Interestingly, it was related to fewer mental health problems primarily through the direct paths rather than social support.

Chia-chen Yang, Paul Hunhoff, Yen Lee, Jonah Abrell

J Med Internet Res 2025;27:e73098

Media Discourse, Influence, and Reflection: Content Analysis and Text-Mining Study of Suicides and Homicides in Long-Term Care

Media Discourse, Influence, and Reflection: Content Analysis and Text-Mining Study of Suicides and Homicides in Long-Term Care

In Taiwan, the promulgation of the “Long-Term Care Services Act” and promotion of Long-Term Care 2.0 have led to widespread use of the term “long-term care.” However, when the news equates “long-term care tragedy” with caregiving homicides, such as “Long-term Care Tragedy! Son Burns Himself and His Mother to Death After Allegedly Experiencing Despair as a Caregiver for Mother with Dialysis” [26] or “Tragic Long-term Care!

Charlotte Wang, Hsiu-Ju Fang, Hsin-Yang Lu, Chen-Fen Chen

J Med Internet Res 2025;27:e59037

Comparing Diagnostic Accuracy of Clinical Professionals and Large Language Models: Systematic Review and Meta-Analysis

Comparing Diagnostic Accuracy of Clinical Professionals and Large Language Models: Systematic Review and Meta-Analysis

There are many internal medicine diseases that require long-term follow-up and monitoring. LLMs can process all historical data of patients simultaneously and updating personalized treatment plans, assisting clinical professionals in making more beneficial decisions [57-59].

Guxue Shan, Xiaonan Chen, Chen Wang, Li Liu, Yuanjing Gu, Huiping Jiang, Tingqi Shi

JMIR Med Inform 2025;13:e64963

Real-Time, Risk-Based Clinical Trial Quality Management in China: Development of a Digital Monitoring Platform

Real-Time, Risk-Based Clinical Trial Quality Management in China: Development of a Digital Monitoring Platform

To meet the urgent need for upgrading quality management models and achieving better efficiency, accuracy, and timeliness, we leveraged the RBQM mindset and used a long-term collection of quality management data from clinical trial programs in Beijing University Cancer Hospital, China, to build a digital dynamic monitoring platform via big data analysis and automatic quantitative technology.

Min Jiang, Shuhua Zhao, Yun Mei, Zhiying Fu, Yannan Yuan, Jie Ai, Yuan Sheng, Ying Gong, Jingjing Chen

JMIR Med Inform 2025;13:e64114

Effect of Digital Exercise Therapy on the Pain and Physical Function of Patients With Osteoarthritis: Systematic Review and Meta-Analysis

Effect of Digital Exercise Therapy on the Pain and Physical Function of Patients With Osteoarthritis: Systematic Review and Meta-Analysis

Our findings align with a previous review of digital therapeutic tools for exercise programs in knee OA [38], which reported significant pain improvements in 10 of 11 studies but did not address long-term outcomes. This underscores the potential of digital modalities for short-term symptom management while highlighting the need for strategies to prolong therapeutic effects. The loss of effect at follow-up is an important finding that warrants further exploration.

Jing Long, Jikai You, Yanan Yang

J Med Internet Res 2025;27:e66037

CoVimmune COVID-19 Immunity Calculator: Web Application Development and Validation Study

CoVimmune COVID-19 Immunity Calculator: Web Application Development and Validation Study

The first dataset was derived from a prospective cohort study which measured anti-SARS-COV-2 n Ab half-maximal inhibitory concentration (IC50) titers against pseudotyped WA-1 (the original SARS-Co V-2 strain) at specific time periods over a year-long interval following the primary messenger RNA vaccination series and a subsequent booster vaccine dose (before dose 1, before dose 2, and after dose 2 at 1, 3, 6, and 12 months, with an additional collection 1 month after dose 3, which was approximately 10 months after

Rebecca Slotkin, Tassos C Kyriakides, Vinni Yu, Xien Chen, Anupam Kundu, Shaili Gupta

JMIR Form Res 2025;9:e59467

Effects of an e-Learning Program (Physiotherapy Exercise and Physical Activity for Knee Osteoarthritis [PEAK]) on Chinese Physical Therapists’ Confidence and Knowledge: Randomized Controlled Trial

Effects of an e-Learning Program (Physiotherapy Exercise and Physical Activity for Knee Osteoarthritis [PEAK]) on Chinese Physical Therapists’ Confidence and Knowledge: Randomized Controlled Trial

Thus, future behavior change interventions for Chinese practitioners should emphasize the development of transdisciplinary core capabilities [44] to enhance person-centered approaches to achieve long-term health outcomes. Most participants emphasized the importance of scans, likely due to their routine availability in Chinese public hospitals without appointments or long waits.

Zi-Ru Wang, Yunqi Wang, Shuning Duan, Xier Chen, Guoxin Ni

J Med Internet Res 2025;27:e71057

The Effect of a Brief Video-Based Intervention to Improve AIDS Prevention in Older Men: Randomized Controlled Trial

The Effect of a Brief Video-Based Intervention to Improve AIDS Prevention in Older Men: Randomized Controlled Trial

The AIDS educational video used in this study is named Sunset Without AIDS and is 25 minutes long. In conceptualizing the video, the Information-Motivation-Behavioral (IMB) Skills Model was selected. The IMB Skills Model involves three aspects: AIDS-related information, motivation, and behavior skills [34]. It states that knowledge alone is insufficient for behavior change it must be linked to both motivation and behavioral skills to overcome barriers critical to achieving adherence [27].

Tian Huaju, Xie Rendie, Xiao Lu, Li Mei, Luo Yue, Zhang Daiying, Chen Yanhua, Ren Jianlan

JMIR Public Health Surveill 2025;11:e65674