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Our analyses, based on simulated data, suggest that a total sample size of 300 provides enough statistical power (up to 90%) to detect anticipated effect sizes on primary outcomes of cognitive capacity and cognitive bias based on values from our group and those reported in the literature (CR: d=0.50 and MCT: g=0.27) [9,20,27,31]. The attrition rate for our digital groups has been approximately 20%; we will nonetheless conservatively adjust for an attrition rate of 30%.
JMIR Res Protoc 2025;14:e63269
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Sequencing of Methadone Patient Access to Collaborative Treatment (MPACT) primary and secondary measures (assessment 1-5).
a Not applicable.
b SUD: substance use disorder.
c MMT: methadone maintenance treatment.
d OD: opioid overdose.
e LEC: Life Events Checklist.
f PCL-5: Posttraumatic Stress Disorder Checklist.
g Patients only.
h Pro Qo L: Professional Quality of Life Scale.
i ARTIC: attitudes toward trauma-informed care.
j PCQ-S: Patient-Centered Climate Scale for staff.
k OUD: opioid use disorder.
l PCC: person-centered
JMIR Res Protoc 2025;14:e69829
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On average, participants used the app for 12.67 days (SD 9.96 d) of the 28 days of the intervention period.
Overall, providing added incentives did not seem to impact how students used the app to log their drinks. Among those in the phase 2 group, students randomized to receive incentives logged, on average, 11.16 drinks (SD 8.92) while those randomized to receive no added incentives logged, on average, 13.04 drinks (SD 16.62), t130=0.924, and P=.357.
JMIR Hum Factors 2025;12:e69873
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