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Skip search results from other journals and go to results- 639 Journal of Medical Internet Research
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Monte Carlo simulations computed in R (R Foundation for Statistical Computing) were used to estimate the required sample size for our proposed models. Our analyses, based on simulated data, suggest that a total sample size of 300 provides enough statistical power (up to 90%) to detect anticipated effect sizes on primary outcomes of cognitive capacity and cognitive bias based on values from our group and those reported in the literature (CR: d=0.50 and MCT: g=0.27) [9,20,27,31].
JMIR Res Protoc 2025;14:e63269
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The PMIS (Pearson r=−0.76; P
As we examined the sensitivity and specificity data to choose cut scores, we chose to favor sensitivity to minimize missing individuals with true disease in this sample of patients considered high risk because of their cognitive concerns. The cut scores for a positive result on the 5-Cog components were as follows: PMIS ≤6 (range 0-8), Symbol Match ≤25 (range 0-65), and s MCR >5 (range 0-7).
JMIR Res Protoc 2025;14:e60471
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The application of this mapping to the data was performed using R version 4.3.2 (R Foundation for Statistical Computing). The full list of diagnosis names corresponding to ADRD diagnosis categories is provided in Multimedia Appendix 1.
To assess associations between clusters and sex, as well as ADRD diagnoses, we used the chi-square test.
JMIR Aging 2025;8:e65178
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