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Stress Reduction in Perioperative Care: Feasibility Randomized Controlled Trial

Stress Reduction in Perioperative Care: Feasibility Randomized Controlled Trial

According to the study protocol reported by Kondylakis et al [39], participants were randomized to achieve a balance between the 2 groups (intervention and control groups) according to the type of surgery and baseline characteristics (covariates). Considering a 1:1 random allocation, significance level of .05 (2-sided), and 80% power, 60 participants were needed to detect a 10% difference in stress, anxiety, and pain between the intervention and control groups.

Haridimos Kondylakis, Irene Alice Chicchi Giglioli, Dimitrios Katehakis, Hatice Aldemir, Paul Zikas, George Papagiannakis, Santiago Hors-Fraile, Pedro L González-Sanz, Konstantinos Apostolakis, Constantine Stephanidis, Francisco J Núñez-Benjumea, Rosa M Baños-Rivera, Luis Fernandez-Luque, Angelina Kouroubali

J Med Internet Res 2025;27:e54049