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Identifying Intersecting Factors Associated With Suicidal Thoughts and Behaviors Among Transgender and Gender Diverse Adults: Preliminary Conditional Inference Tree Analysis

Identifying Intersecting Factors Associated With Suicidal Thoughts and Behaviors Among Transgender and Gender Diverse Adults: Preliminary Conditional Inference Tree Analysis

Conditional inference trees model the nonlinear relationships between a wide range of predictors and an outcome. As a data mining approach, the conditional inference tree is a data-driven analytic strategy that identifies interacting social determinants from many candidate predictors to determine which predictors are most relevant to specific outcomes.

Amelia M Stanton, Lauren A Trichtinger, Norik Kirakosian, Simon M Li, Katherine E Kabel, Kiyan Irani, Alexandra H Bettis, Conall O’Cleirigh, Richard T Liu, Qimin Liu

J Med Internet Res 2025;27:e65452

Motivation Theories and Constructs in Experimental Studies of Online Instruction: Systematic Review and Directed Content Analysis

Motivation Theories and Constructs in Experimental Studies of Online Instruction: Systematic Review and Directed Content Analysis

For example, medical students completing an online module on a basic science topic may be confident in their ability to learn but struggle to see the value in the material beyond their next examination. Conversely, students completing a virtual examination with a standardized patient may see the value in what they are learning but not feel confident in their ability to succeed.

Adam Gavarkovs, Erin Miller, Jaimie Coleman, Tharsiga Gunasegaran, Rashmi A Kusurkar, Kulamakan Kulasegaram, Melanie Anderson, Ryan Brydges

JMIR Med Educ 2025;11:e64179

A Web-Based Tool to Perform a Values Clarification for Stroke Prevention in Patients With Atrial Fibrillation: Design and Preliminary Testing Study

A Web-Based Tool to Perform a Values Clarification for Stroke Prevention in Patients With Atrial Fibrillation: Design and Preliminary Testing Study

In a wide variety of patients with AF, anticoagulation reduces the risk of ischemic stroke by 65% with a relative 2-fold increase in major extracranial bleeding compared to placebo [1-3]. Yet, medication responses vary across patients.

Michael P Dorsch, Allen J Flynn, Kaitlyn M Greer, Sabah Ganai, Geoffrey D Barnes, Brian Zikmund-Fisher

JMIR Cardio 2025;9:e67956

Maternal Metabolic Health and Mother and Baby Health Outcomes (MAMBO): Protocol of a Prospective Observational Study

Maternal Metabolic Health and Mother and Baby Health Outcomes (MAMBO): Protocol of a Prospective Observational Study

The aim of this study is to develop risk calculators that best predict (1) a mother’s risk of having a neonate with abnormal fetal growth (large for gestational age [LGA] or small for gestational age [SGA]); (2) a mother’s risk of having a serious adverse neonatal outcome; and (3) a mother’s risk of developing new metabolic disease after pregnancy (Figure 1).

Sarah A L Price, Digsu N Koye, Alice Lewin, Alison Nankervis, Stefan C Kane

JMIR Res Protoc 2025;14:e72542

Sociodemographic Differences in Logins and Engagement With the Electronic Health Coach Messaging Feature of a Mobile App to Support Opioid and Stimulant Use Recovery: Results From a 1-Month Observational Study

Sociodemographic Differences in Logins and Engagement With the Electronic Health Coach Messaging Feature of a Mobile App to Support Opioid and Stimulant Use Recovery: Results From a 1-Month Observational Study

To be eligible for inclusion in the u MAT-R intervention program, individuals had to: (1) report a history of or current opioid or stimulant misuse; (2) be in treatment at one of the included recruitment facilities; (3) be 18 years or older; (4) be a US resident; (5) be fluent in English; and (6) own or have access to a smartphone with an i OS or Android operating system.

Lindsey M Filiatreau, Hannah Szlyk, Alex T Ramsey, Erin Kasson, Xiao Li, Zhuoran Zhang, Patricia Cavazos-Rehg

JMIR Mhealth Uhealth 2025;13:e54753

Comparison of Deep Learning Approaches Using Chest Radiographs for Predicting Clinical Deterioration: Retrospective Observational Study

Comparison of Deep Learning Approaches Using Chest Radiographs for Predicting Clinical Deterioration: Retrospective Observational Study

Furthermore, this simplifies the prediction task to a single time point, making it more feasible to compare multiple models and augmentation strategies. Patients with a chest radiograph within 48 hours before the first elevated e CART score were included in the study. Available anterior-posterior or posterior-anterior views were included in the study cohort.

Mahmudur Rahman, Jifan Gao, Kyle A Carey, Dana P Edelson, Askar Afshar, John W Garrett, Guanhua Chen, Majid Afshar, Matthew M Churpek

JMIR AI 2025;4:e67144

Effects of Using a Smart Bassinet on the Mental Health of Military-Affiliated Pregnant Women: Protocol for a Randomized Controlled Sleep Health and Mood in Newly Expectant Military Mothers (SHINE) Trial

Effects of Using a Smart Bassinet on the Mental Health of Military-Affiliated Pregnant Women: Protocol for a Randomized Controlled Sleep Health and Mood in Newly Expectant Military Mothers (SHINE) Trial

The inclusion criteria were pregnant military-affiliated individuals with a singleton gestation; age 18-45 years; ability to communicate in English during the screening process; access to a computer, smartphone, or tablet with internet service; willing to use the bassinet they are randomized to; and willing to travel to a local Quest Diagnostics (an insert description) for blood draw.

Michele L Okun, Jennifer L Payne, Lauren M Osborne, Leilani Feliciano, Andrew Lac

JMIR Res Protoc 2025;14:e66439

Examining a Telemedicine-Based Virtual Reality Clinic in Treating Adults With Specific Phobia: Protocol for a Feasibility Randomized Controlled Efficacy Trial

Examining a Telemedicine-Based Virtual Reality Clinic in Treating Adults With Specific Phobia: Protocol for a Feasibility Randomized Controlled Efficacy Trial

Doxy.me VR is designed for a therapist to meet with a client remotely in a private, comfortable VR clinic that looks and feels like a therapist’s office (refer to Figure 1 for screenshots of the clinic). To join the VR session, the therapist provides their unique, persistent 4-digit room code to their client, who enters the code to check in. Once the therapist admits the client, they can interact by speaking and gesturing with each other in immersive VR.

Kaitlyn R Schuler, Triton Ong, Brandon M Welch, Jason G Craggs, Brian E Bunnell

JMIR Res Protoc 2025;14:e65770

Association of Social Media Recruitment and Depression Among Racially and Ethnically Diverse Metabolic and Bariatric Surgery Candidates: Prospective Cohort Study

Association of Social Media Recruitment and Depression Among Racially and Ethnically Diverse Metabolic and Bariatric Surgery Candidates: Prospective Cohort Study

Of these, MBS is a safe and effective treatment option, particularly for individuals with severe obesity who are resistant to other interventions [4]. A 2014 meta-analysis of 164 studies involving 160,000 patients found that BMI decreased by at least 11.8 kg/m² one-year post MBS, with sustained weight loss observed five years post surgery [5].

Jackson M Francis, Sitapriya S Neti, Dhatri Polavarapu, Folefac Atem, Luyu Xie, Olivia Kapera, Matthew S Mathew, Elisa Marroquin, Carrie McAdams, Jeffrey Schellinger, Sophia Ngenge, Sachin Kukreja, Benjamin E Schneider, Jaime P Almandoz, Sarah E Messiah

JMIR Form Res 2025;9:e58916

Provider Perspectives on Implementing an Enhanced Digital Screening for Adolescent Depression and Suicidality: Qualitative Study

Provider Perspectives on Implementing an Enhanced Digital Screening for Adolescent Depression and Suicidality: Qualitative Study

Transcripts were coded by the first author following a template analysis approach [18] with NVivo software (version 14; Lumivero), using a prespecified codebook. The codebook was created according to a hybrid approach, using a deductive approach to generate high-level codes based on the CFIR Codebook Template [15], and an inductive approach to incorporate themes that arose from the data [19].

Morgan A Coren, Oliver Lindhiem, Abby R Angus, Emma K Toevs, Ana Radovic

JMIR Form Res 2025;9:e67624