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AI-Based Identification Method for Cervical Transformation Zone Within Digital Colposcopy: Development and Multicenter Validation Study

AI-Based Identification Method for Cervical Transformation Zone Within Digital Colposcopy: Development and Multicenter Validation Study

Current evaluation studies [10,11] have demonstrated that junior or less-experienced colposcopists can detect abnormal cervical lesions more effectively with AI assistance, which indicates its potential to help reduce missed diagnoses. However, the functions of AI cannot be limited. All colposcopic features were the indicators for assessing colposcopist performance.

Tong Wu, Yuting Wang, Xiaoli Cui, Peng Xue, Youlin Qiao

JMIR Cancer 2025;11:e69672

Exploring the Discontinuous Usage Behavior of Digital Cognitive Training Among Older Adults With Mild Cognitive Impairment and Their Family Members: Qualitative Study Using the Extended Model of IT Continuance

Exploring the Discontinuous Usage Behavior of Digital Cognitive Training Among Older Adults With Mild Cognitive Impairment and Their Family Members: Qualitative Study Using the Extended Model of IT Continuance

I don't know (what can improve memory) anymore, maybe participate in activities. Is there a way to improve (memory)? Does such a thing exist? (asked with confusion and urgency) Negative experiences during the training process can hinder older adults with MCI from actively trying again, reducing their interest and motivation in training games.

Shangyang Zhang, Min Wu, Ruini Sun, Changjie Cui, Ziqing Zhang, Jing Liao, Ni Gong

J Med Internet Res 2025;27:e66393

Clinical Safety of Pudilan Xiaoyan Oral Liquid for the Treatment of Upper Respiratory Tract Infection in the Real World: Protocol for a Prospective, Observational, Registry Study

Clinical Safety of Pudilan Xiaoyan Oral Liquid for the Treatment of Upper Respiratory Tract Infection in the Real World: Protocol for a Prospective, Observational, Registry Study

Additionally, S baicalensis exhibits limited embryotoxicity and hepatotoxicity and can induce allergic reactions leading to vesicular eruptions [9]. T mongolicum primarily contributes to reversible toxicity targeting red blood cells [10], while I indigotica possesses nephrotoxic properties and may impose a burden on the urinary system with prolonged use [11]. The formulation of C bungeana contains certain hepatotoxic effects [12].

Mengmeng Wang, Lianxin Wang, Fumei Liu, Renbo Chen, Zhifei Wang, Xin Cui, Yuanyuan Li, Yanming Xie

JMIR Res Protoc 2025;14:e65789

Caregiving Artificial Intelligence Chatbot for Older Adults and Their Preferences, Well-Being, and Social Connectivity: Mixed-Method Study

Caregiving Artificial Intelligence Chatbot for Older Adults and Their Preferences, Well-Being, and Social Connectivity: Mixed-Method Study

Such progress can potentially address older adults’ concerns with existing technologies and improve their experience using these technologies. Recent developments have focused on creating AI technologies specifically for older adults, aiming to address their needs for companionship, support, and health management. Senior Talk [15], for example, offers an AI-powered chat companion that can be personalized through the selection of different personas.

Brooke H Wolfe, Yoo Jung Oh, Hyesun Choung, Xiaoran Cui, Joshua Weinzapfel, R Amanda Cooper, Hae-Na Lee, Rebecca Lehto

J Med Internet Res 2025;27:e65776

Correlation Between the Online Visiting Time and Frequency Increase in Telemedicine Services Offered by Health Care Providers Before, During, and After the COVID-19 Pandemic in China: Cross-Sectional Study

Correlation Between the Online Visiting Time and Frequency Increase in Telemedicine Services Offered by Health Care Providers Before, During, and After the COVID-19 Pandemic in China: Cross-Sectional Study

In our results, public providers reported that a higher frequency increase after pandemic controls were relaxed might be because public hospitals, especially tertiary public hospitals in China, usually have a better reputation, whereas private third-party telemedicine platforms or physicians who work a “part-time job” on these platforms can hardly acquire patient trust.

Weiyi Wang, Yuntian Chu, Fangfang Cui, Xiaobing Shi, Xu Zhang, Dongxu Sun, Jinming Shi, Jie Zhao

J Med Internet Res 2025;27:e65092

A Risk Warning Model for Anemia Based on Facial Visible Light Reflectance Spectroscopy: Cross-Sectional Study

A Risk Warning Model for Anemia Based on Facial Visible Light Reflectance Spectroscopy: Cross-Sectional Study

Raman spectroscopy can be used to analyze the distribution of metabolite, lipid, protein, water, and blood content in tissues by detecting the skin[20]. Hyperspectral imaging can estimate Hb concentration and blood oxygen saturation by diffuse reflection of tissues [21]. Spectral imaging of sublingual microcirculation was proven to be able to detect anemia [22]. Research on noninvasive Hb measurement using spectroscopy predominantly focuses on areas such as the palm, fingernails, and conjunctiva.

Yahan Zhang, Yi Chun, Hongyuan Fu, Wen Jiao, Jizhang Bao, Tao Jiang, Longtao Cui, Xiaojuan Hu, Ji Cui, Xipeng Qiu, Liping Tu, Jiatuo Xu

JMIR Med Inform 2025;13:e64204

Long-Term Exposure to Fine Particulate Matter (PM2.5) Components and Precocious Puberty Among School-Aged Children: Cross-Sectional Study

Long-Term Exposure to Fine Particulate Matter (PM2.5) Components and Precocious Puberty Among School-Aged Children: Cross-Sectional Study

Some animal studies have found that fructose diet–fed rats had lower plasma testosterone levels, which can lead to a high sensitivity of the pituitary-gonadal axis in Leydig cells [51]. It can be speculated that dietary factors may potentially involve pathways that overlap with PM2.5 and promote or hinder the effects of PM2.5 on precocious puberty.

Xuelian Zhou, Xiaochi Zhang, Guannan Bai, Guanping Dong, Xinyi Li, Ruimin Chen, Shaoke Chen, Rongxiu Zheng, Chunlin Wang, Haiyan Wei, Bingyan Cao, Yan Liang, Hui Yao, Zhe Su, Mireguli Maimaiti, Feihong Luo, Pin Li, Min Zhu, Hongwei Du, Yu Yang, Lanwei Cui, Jinling Wang, Jinna Yuan, Zhuang Liu, Wei Wu, Qi Zhao, Junfen Fu

JMIR Public Health Surveill 2025;11:e62861

Women Empowered to Connect With Addiction Resources and Engage in Evidence-Based Treatment (WE-CARE)—an mHealth Application for the Universal Screening of Alcohol, Substance Use, Depression, and Anxiety: Usability and Feasibility Study

Women Empowered to Connect With Addiction Resources and Engage in Evidence-Based Treatment (WE-CARE)—an mHealth Application for the Universal Screening of Alcohol, Substance Use, Depression, and Anxiety: Usability and Feasibility Study

Substance use during pregnancy can also elevate the risk of miscarriage, fetal alcohol syndrome, and birth defects [5]. The US Preventative Task Force (USPTF) reported that about 50% of US pregnancies are unplanned or unintended, with women between the ages of 18-24 facing a higher risk of unplanned pregnancies [6]. As such, alcohol and substance use during pregnancy can pose a combination of risks and potential consequences for both the mother and baby, including fetal alcohol spectrum disorders [7,8].

Krystyna Isaacs, Autumn Shifflett, Kajal Patel, Lacey Karpisek, Yi Cui, Maayan Lawental, Golfo Tzilos Wernette, Brian Borsari, Katie Chang, Tony Ma

JMIR Form Res 2025;9:e62915