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Effects of a Monophasic Hormonal Contraceptive With Norgestimate+Ethinyl Estradiol on Menstrual Bleeding: Protocol and Design of a Multicenter, Prospective, Open-Label, Noncomparative Study in Italy

Effects of a Monophasic Hormonal Contraceptive With Norgestimate+Ethinyl Estradiol on Menstrual Bleeding: Protocol and Design of a Multicenter, Prospective, Open-Label, Noncomparative Study in Italy

any 1 of these disqualifies an individual from participating) Any contraindications to the use of combined oral contraceptives (COCs) according to the current summary of product characteristics of Effimia, that is, women presenting (or having ever presented) with myocardial infarction, transient ischemic attack, stroke, angina pectoris, deep vein thrombosis, pulmonary embolism (or presence of blood clots in organs other than legs and lungs), any blood clotting disorder (such as protein C deficiency, protein S

Angelo Cagnacci, Giovanni Grandi, Giampiero Capobianco, Anna Maria Fulghesu, Giuseppe Morgante, Vincenzo Biondelli, Elena Piccolo, Elena Casolati, Mario Mangrella

JMIR Res Protoc 2025;14:e63683