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Family Caregiver Perspectives on Digital Methods to Measure Stress: Qualitative Descriptive Study

Family Caregiver Perspectives on Digital Methods to Measure Stress: Qualitative Descriptive Study

Demographics of interview participants (N=27). a Others comprise frailty, Parkinson disease, and stroke. We identified 3 themes with 10 subthemes (Table 2). The 3 themes were “providing meaningful data,” “low-burden monitoring,” and “inadvertent harms of stress monitoring.” in the later sections, we discuss these themes and their subthemes as they applied to the more general concept of using technology to monitor stress and more specifically to EMA, RMT, and fluid biosensors.

Louise Rose, Sian Saha, Emily Flowers, Chee Siang Ang, Alexander J Casson, Joan Condell, Faith Matcham, Tony Robinson, John Rooksby

J Med Internet Res 2025;27:e66034

The Fire Fighter Cancer Cohort Study: Protocol for a Longitudinal Occupational Cohort Study

The Fire Fighter Cancer Cohort Study: Protocol for a Longitudinal Occupational Cohort Study

The Fire Fighter Cancer Cohort Study participants’ demographics and department type (N=6200). a Some firefighters (n=28) are both wildland and airport firefighters. The average age of participating firefighters is 37.8 (SD 11) years, including the age of recruits at enrollment (mean 29.3, SD 5 years) and the age of incumbents at enrollment (mean 40.3, SD 11 years).

Jefferey L Burgess, Shawn C Beitel, Miriam M Calkins, Melissa A Furlong, Paola Louzado Feliciano, Jamie Kolar Gabriel, Casey Grant, Jaclyn M Goodrich, Judith M Graber, Olivia Healy, James Hollister, Jeff Hughes, Sara Jahnke, Krystal Kern, Frank A Leeb, Alberto J Caban-Martinez, Alexander C Mayer, Russell Osgood, Cynthia Porter, Sreenivasan Ranganathan, Heather M Stapleton, Natasha Schaefer Solle, Christine Toennis, Derek J Urwin, Michelle Valenti, John J Gulotta

JMIR Res Protoc 2025;14:e70522

Development and Systematic Evaluation of a Progressive Web Application for Women With Cardiac Pain: Usability Study

Development and Systematic Evaluation of a Progressive Web Application for Women With Cardiac Pain: Usability Study

At heart (formerly HEARTPA♀N) [29], a self-management progressive web application, was developed for women with CAD using a sequential phased approach recommended by the Medical Research Council (MRC) [30-32]. In phase 1, an integrated mixed methods systematic review was conducted to evaluate the current evidence related to the self-management of cardiac pain and associated symptoms (eg, dyspnea and fatigue) in women [7,29].

Monica Parry, Tony Huang, Hance Clarke, Ann Kristin Bjørnnes, Paula Harvey, Laura Parente, Colleen Norris, Louise Pilote, Jennifer Price, Jennifer N Stinson, Arland O’Hara, Madusha Fernando, Judy Watt-Watson, Nicole Nickerson, Vincenza Spiteri DeBonis, Donna Hart, Christine Faubert

JMIR Hum Factors 2025;12:e57583

Greater Improvements in Vaccination Outcomes Among Black Young Adults With Vaccine-Resistant Attitudes in the United States South Following a Digital Health Intervention: Latent Profile Analysis of a Randomized Control Trial

Greater Improvements in Vaccination Outcomes Among Black Young Adults With Vaccine-Resistant Attitudes in the United States South Following a Digital Health Intervention: Latent Profile Analysis of a Randomized Control Trial

A total of 360 Black young adults were included in this study, of whom 76% (n=272) identified as cisgender or transgender women. The median age was 24 (IQR 21‐27) years, and approximately one-third of participants (n=122) had a bachelor’s degree or higher. Overall vaccine uptake at month 3 was low (n=21) and did not significantly differ between the intervention and control arms (odds ratio [OR] 1.88, 95% CI 0.76 to 4.69).

Noah Mancuso, Jenna Michaels, Erica N Browne, Allysha C Maragh-Bass, Jacob B Stocks, Zachary R Soberano, C Lily Bond, Ibrahim Yigit, Maria Leonora G Comello, Margo Adams Larsen, Kathryn E Muessig, Audrey Pettifor, Lisa B Hightow-Weidman, Henna Budhwani, Marie C D Stoner

JMIR Public Health Surveill 2025;11:e67370

Mental Health Apps Available in App Stores for Indian Users: Protocol for a Systematic Review

Mental Health Apps Available in App Stores for Indian Users: Protocol for a Systematic Review

Features of interactive self-care apps (N=33) were reviewed further, and this exercise showed that less than 10% of the apps incorporated explicit delineation of their scope or initial screening for suitability. Slightly more than one-third of these apps included content aimed at encouraging professional help-seeking when needed or an explicit mention of their theoretical or empirical basis. Challenges for potential users were highlighted [20].

Seema Mehrotra, Ravikesh Tripathi, Pramita Sengupta, Abhishek Karishiddimath, Angelina Francis, Pratiksha Sharma, Paulomi Sudhir, Srikanth TK, Girish N Rao, Rajesh Sagar

JMIR Res Protoc 2025;14:e71071

Bridging Data Silos in Oncology with Modular Software for Federated Analysis on Fast Healthcare Interoperability Resources: Multisite Implementation Study

Bridging Data Silos in Oncology with Modular Software for Federated Analysis on Fast Healthcare Interoperability Resources: Multisite Implementation Study

The 10 most frequent cancer diagnoses included prostate cancer (n=2476, 13.8%); breast cancer (n=2006, 11.2%); malignant melanoma of the skin (n=1921, 10.7%); cancer of the trachea, bronchus, and lungs (n=1415, 7.9%); cancer of the lip, oral cavity, and pharynx (n=1329, 7.4%); and cancer of the colon and rectum (n=1187, 6.6%). Non-Hodgkin lymphoma (n=801), cervical cancer (n=719), pancreatic cancer (n=644), and thyroid cancer each accounted for 4%.

Jasmin Ziegler, Marcel Pascal Erpenbeck, Timo Fuchs, Anna Saibold, Paul-Christian Volkmer, Guenter Schmidt, Johanna Eicher, Peter Pallaoro, Renata De Souza Falguera, Fabio Aubele, Marlien Hagedorn, Ekaterina Vansovich, Johannes Raffler, Stephan Ringshandl, Alexander Kerscher, Julia Karolin Maurer, Brigitte Kühnel, Gerhard Schenkirsch, Marvin Kampf, Lorenz A Kapsner, Hadieh Ghanbarian, Helmut Spengler, Iñaki Soto-Rey, Fady Albashiti, Dirk Hellwig, Maximilian Ertl, Georg Fette, Detlef Kraska, Martin Boeker, Hans-Ulrich Prokosch, Christian Gulden

J Med Internet Res 2025;27:e65681

Methadone Patient Access to Collaborative Treatment: Protocol for a Pilot and a Randomized Controlled Trial to Establish Feasibility of Adoption and Impact on Methadone Treatment Delivery and Patient Outcomes

Methadone Patient Access to Collaborative Treatment: Protocol for a Pilot and a Randomized Controlled Trial to Establish Feasibility of Adoption and Impact on Methadone Treatment Delivery and Patient Outcomes

We evaluate the number of clinics and number of patients, assuming that MPACT intervention reduces this frequency to 45% (n=240), 50% (n=300), and 55% (n=330). The power curves based on independent observations (no cluster effect) are shown in Figure 3. The graph shows that the recruitment of 30 clinics, with 20 patients per clinic, provides greater than 80% power to detect a difference in treatment interruption rates of 66% (control) and 55% (MPACT) with α=.05.

Beth E Meyerson, Alissa Davis, Richard A Crosby, Linnea B Linde-Krieger, Benjamin R Brady, Gregory A Carter, Arlene N Mahoney, David Frank, Janet Rothers, Zhanette Coffee, Elana Deuble, Jonathon Ebert, Mary F Jablonsky, Marlena Juarez, Barbara Lee, Heather M Lorenz, Michael D Pava, Kristen Tinsely, Sana Yousaf

JMIR Res Protoc 2025;14:e69829

Maternal Metabolic Health and Mother and Baby Health Outcomes (MAMBO): Protocol of a Prospective Observational Study

Maternal Metabolic Health and Mother and Baby Health Outcomes (MAMBO): Protocol of a Prospective Observational Study

Given the anticipated overlap of these conditions, ≈20% (n=90) of women will have at least one maternal metabolic disease of interest (secondary outcome). Study data are collected using paper case report forms. These paper documents will be kept in a locked cupboard accessible only to local research staff. Patient information is collected and stored by the investigators in a confidential REDCap (Research Electronic Data Capture system; Vanderbilt University), with password protection and restricted access.

Sarah A L Price, Digsu N Koye, Alice Lewin, Alison Nankervis, Stefan C Kane

JMIR Res Protoc 2025;14:e72542