Validation of 3 Computer-Aided Facial Phenotyping Tools (DeepGestalt, GestaltMatcher, and D-Score): Comparative Diagnostic Accuracy Study

Alisa Maria Vittoria Reiter   ¹ ;   Jean Tori Pantel   ^{1, 2, 3} ;   Magdalena Danyel   ^{1, 4, 5} , MD ;   Denise Horn   ¹ , Prof Dr ;   Claus-Eric Ott   ¹ , MD ;   Martin Atta Mensah   ^{1, 6} , MD

¹ Institute of Medical Genetics and Human Genetics, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany

² Institute for Digitalization and General Medicine, University Hospital Aachen, Aachen, Germany

³ Center for Rare Diseases Aachen ZSEA, University Hospital Aachen, Aachen, Germany

⁴ BIH Biomedical Innovation Academy, Clinician Scientist Program, Berlin Institute of Health at Charité–Universitätsmedizin Berlin, Berlin, Germany

⁵ Berlin Center for Rare Diseases, Charité - Universitätsmedizin Berlin corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany

⁶ BIH Biomedical Innovation Academy, Digital Clinician Scientist Program, Berlin Institute of Health at Charité–Universitätsmedizin Berlin, Berlin, Germany