The Effect of Integration of Self-Management Web Platforms on Health Status in Chronic Obstructive Pulmonary Disease Management in Primary Care (e-Vita Study): Interrupted Time Series Design

Esther PWA Talboom-Kamp   ^{1, 2} , MBA, MD ;   Noortje A Verdijk   ^{1, 2} , MSc, PhD ;   Marise J Kasteleyn   ¹ , MSc, PhD ;   Lara M Harmans   ² , MSc ;   Irvin JSH Talboom   ³ ;   Ingrid Looijmans-van den Akker   ⁴ , MD, PhD ;   Nan van Geloven   ⁵ , MSc, PhD ;   Mattijs E Numans   ¹ , MD, PhD ;   Niels H Chavannes   ¹ , MD, PhD

¹ Leiden University Medical Center, Public Health and Primary Care Department, Leiden, Netherlands

² Saltro Diagnostic Center, Utrecht, Netherlands

³ Zorgdraad Foundation, Oosterbeek, Netherlands

⁴ Leidsche Rijn Julius Healthcare Centers, location Terwijde, Utrecht, Netherlands

⁵ Leiden University Medical Center, Department of Medical Statistics and Bioinformatics, Leiden, Netherlands