TY - JOUR AU - Ong, Anthony AU - Wilcox, Kenneth AU - Reid, M Carrington AU - Wethington, Elaine AU - Cintron, Dakota AU - Addington, Elizabeth AU - Goktas, Selin AU - Moskowitz, Judith PY - 2024 DA - 2024/12/10 TI - Targeting Daily Positive Events to Improve Emotional and Functional Well-Being in Adults With Fibromyalgia: Insights From the LARKSPUR Randomized Controlled Trial JO - J Med Internet Res SP - e54678 VL - 26 KW - positive affect KW - chronic pain KW - chronic condition KW - long-term pain KW - positive psychology KW - positive events KW - fibromyalgia KW - mHealth KW - app KW - digital technology KW - digital interventions KW - gerontology KW - geriatrics KW - older adult KW - aging KW - well-being AB - Background: Fibromyalgia is a chronic pain condition characterized by widespread musculoskeletal pain, fatigue, and cognitive difficulties, affecting individuals across all age groups. Positive affect (PA) interventions have shown promise in enhancing emotional well-being and pain management in patients with diverse chronic pain conditions. However, the efficacy of internet-delivered PA interventions for individuals with fibromyalgia remains understudied. Objective: This randomized controlled trial investigated the efficacy of a web-based PA regulation intervention—Lessons in Affect Regulation to Keep Stress and Pain Under Control (LARKSPUR)—in enhancing emotional and functional well-being among adults with fibromyalgia syndrome. Methods: A total of 95 participants with fibromyalgia syndrome aged 50 years and older (89/95, 94% female) were randomized to one of two fully automated conditions: (1) LARKSPUR (n=49) or (2) emotion reporting/attention control (n=46). At the postintervention and 1-month follow-up time points, participants completed 7 consecutive, end-of-day, web-based reports capturing positive events (PE), pain, fatigue, PA, and negative affect. Results: Compared to control, LARKSPUR resulted in greater improvements in daily affective responsivity to PE at the postintervention time point, including greater reductions in negative affect (bL–bC=–0.06, 95% highest posterior density interval [HPD] –0.10 to –0.02) and increases in PA (bL–bC=0.10, 95% HPD 0.02-0.19). Furthermore, across the postintervention and 1-month follow-up time points, LARKSPUR led to greater reductions in pain (bL–bC=–0.20, 95% HPD –0.36 to –0.04) and fatigue (bL–bC=–0.24, 95% HPD –0.41 to –0.06) following PE. Conclusions: This randomized controlled trial provides initial evidence that a web-based PA skills intervention can enhance emotional well-being and reduce pain and fatigue in aging adults with fibromyalgia. Trial Registration: ClinicalTrials.gov NCT04869345; https://clinicaltrials.gov/study/NCT04869345 SN - 1438-8871 UR - https://www.jmir.org/2024/1/e54678 UR - https://doi.org/10.2196/54678 DO - 10.2196/54678 ID - info:doi/10.2196/54678 ER -