TY - JOUR AU - Liu, Wenhua AU - Wang, Quan AU - Zheng, Danli AU - Mei, Junhua AU - Lu, Jiajia AU - Chen, Guohua AU - Wang, Wei AU - Ding, Fengfei PY - 2024 DA - 2024/7/12 TI - The Effects of a Complex Interactive Multimodal Intervention on Personalized Stress Management Among Health Care Workers in China: Nonrandomized Controlled Study JO - J Med Internet Res SP - e45422 VL - 26 KW - multimodal intervention KW - stress management KW - health care workers KW - perceived stress KW - autonomic nervous system KW - stress KW - management KW - mental health KW - engagement KW - human support KW - physiological stress KW - psychological stress KW - social network KW - mobile phone AB - Background: Health care workers (HCWs) frequently face multiple stressors at work, particularly those working night shifts. HCWs who have experienced distress may find it difficult to adopt stress management approaches, even if they are aware of the effects of stress and coping processes. Therefore, an individualized intervention may be required to assist distressed HCWs in bridging the “knowledge-practice” gap in stress management and effectively alleviating stress symptoms. Objective: The main objective of this research was to compare the effects of a complex interactive multimodal intervention (CIMI) to self-guided stress management interventions on stress symptoms of distressed HCWs, as measured by physiological (heart rate variability), psychological (perceived stress, mental distress, and subjective happiness), and sleep disorder (fatigue and sleepiness) indicators. Methods: We conducted a nonrandomized, controlled study in 2 Chinese general hospitals. The participants in this study were 245 HCWs who fulfilled at least 1 of the 3 dimensions on the Depression, Anxiety, and Stress Scale. All eligible individuals were required to complete a questionnaire and wear a 24-hour Holter device to determine the physiological signs of stress as indexed by heart rate variability at both baseline and after the intervention. The CIMI group received a 12-week online intervention with 4 components—mobile stress management instruction, a web-based WeChat social network, personalized feedback, and a nurse coach, whereas the control group simply received a self-guided intervention. Results: After a 12-week intervention, the Perceived Stress Scale (PSS) scores reduced significantly in the CIMI group (mean difference [MD] –5.31, 95% CI –6.26 to –4.37; P<.001) compared to the baseline levels. The changes in PSS scores before and after the intervention exhibited a significant difference between the CIMI and control groups (d=–0.64; MD –4.03, 95% CI –5.91 to –2.14; P<.001), and the effect was medium. In terms of physiological measures, both the control group (MD –9.56, 95% CI –16.9 to –2.2; P=.01) and the CIMI group (MD –8.45, 95% CI –12.68 to –4.22; P<.001) demonstrated a significant decrease in the standard deviation of normal-to-normal intervals (SDNN) within the normal clinical range; however, there were no significant differences between the 2 groups (d=0.03; MD 1.11, 95% CI –7.38 to 9.59; P=.80). Conclusions: The CIMI was an effective intervention for improving sleep disorders, as well as parts of the psychological stress measures in distressed HCWs. The findings provide objective evidence for developing a mobile stress management intervention that is adaptable and accessible to distressed HCWs, but its long-term effects should be investigated in future research. Trial Registration: ClinicalTrials.gov NCT05239065; https://clinicaltrials.gov/ct2/show/NCT05239065 SN - 1438-8871 UR - https://www.jmir.org/2024/1/e45422 UR - https://doi.org/10.2196/45422 DO - 10.2196/45422 ID - info:doi/10.2196/45422 ER -