TY  - JOUR
AU  - Karpov, Boris
AU  - Lipsanen, Jari Olavi
AU  - Ritola, Ville
AU  - Rosenström, Tom
AU  - Saarni, Suoma
AU  - Pihlaja, Satu
AU  - Stenberg, Jan-Henry
AU  - Laizane, Paula
AU  - Joffe, Grigori
PY  - 2023
DA  - 2023/8/17
TI  - The Overall Anxiety Severity and Impairment Scale as an Outcome Measure in Internet-Delivered Cognitive Behavioral Therapy for Anxiety Disorders: Observational Study
JO  - J Med Internet Res
SP  - e45362
VL  - 25
KW  - Overall Anxiety Severity and Impairment Scale
KW  - OASIS
KW  - internet-delivered cognitive behavioral therapy
KW  - iCBT
KW  - anxiety
KW  - social anxiety disorder
KW  - panic disorder
KW  - obsessive-compulsive disorder
KW  - OCD
AB  - Background: Internet-delivered cognitive behavioral therapy (iCBT) is effective in the treatment of anxiety disorders. iCBT clinical trials use relatively long and time-consuming disorder-specific rather than transdiagnostic anxiety measurements. Overall Anxiety Severity and Impairment Scale (OASIS) is a brief self-report scale that could offer a universal, easy-to-use anxiety measurement option in disorder-specific and transdiagnostic iCBT programs. Objective: We aimed to investigate relationships between OASIS and disorder-specific instruments in iCBT. We expected these relationships to be positive. Methods: We investigated patients in original nationwide iCBT programs for generalized anxiety disorder (GAD), obsessive-compulsive disorder, panic disorder, and social anxiety disorder, which were administered by Helsinki University Hospital, Finland. In each program, anxiety symptoms were measured using both disorder-specific scales (the 7-item Generalized Anxiety Disorder scale, Penn State Worry Questionnaire, revised Obsessive-Compulsive Inventory, Panic Disorder Severity Scale, and Social Phobia Inventory) and by OASIS. A general linear model for repeated measures (mixed models) and interaction analysis were used for investigating the changes and relationships in the mean scores of OASIS and disorder-specific scales from the first session to the last one. Results: The main effect of linear mixed models indicated a distinct positive association between OASIS and disorder-specific scale scores. Interaction analysis demonstrated relatively stable associations between OASIS and the revised Obsessive-Compulsive Inventory (F822.9=0.09; 95% CI 0.090-0.277; P=.32), and OASIS and the Panic Disorder Severity Scale (F596.6=–0.02; 95% CI –0.108 to –0.065; P=.63) from first the session to the last one, while the 7-item Generalized Anxiety Disorder scale (F4345.8=–0.06; 95% CI –0.109 to –0.017; P=.007), Penn State Worry Questionnaire (F4270.8=–0.52; 95% CI –0.620 to –0.437; P<.001), and Social Phobia Inventory (F862.1=–0.39; 95% CI –0.596 to –0.187; P<.001) interrelated with OASIS more strongly at the last session than at the first one. Conclusions: OASIS demonstrates clear and relatively stable associations with disorder-specific symptom measures. Thus, OASIS might serve as an outcome measurement instrument for disorder-specific and plausibly transdiagnostic iCBT programs for anxiety disorders in regular clinical practice. 
SN  - 1438-8871
UR  - https://www.jmir.org/2023/1/e45362
UR  - https://doi.org/10.2196/45362
UR  - http://www.ncbi.nlm.nih.gov/pubmed/37590055
DO  - 10.2196/45362
ID  - info:doi/10.2196/45362
ER  -