TY  - JOUR
AU  - Hesseldal, Laura
AU  - Christensen, Jeanette Reffstrup
AU  - Olesen, Thomas Bastholm
AU  - Olsen, Michael Hecht
AU  - Jakobsen, Pernille Ravn
AU  - Laursen, Ditte Hjorth
AU  - Lauridsen, Jørgen Trankjær
AU  - Nielsen, Jesper Bo
AU  - Søndergaard, Jens
AU  - Brandt, Carl Joakim
PY  - 2022
DA  - 2022/9/23
TI  - Long-term Weight Loss in a Primary Care–Anchored eHealth Lifestyle Coaching Program: Randomized Controlled Trial
JO  - J Med Internet Res
SP  - e39741
VL  - 24
IS  - 9
KW  - obesity
KW  - digital behavioral coaching
KW  - health behavior change
KW  - interactive advice
KW  - lifestyle change
KW  - mobile intervention
KW  - patient engagement
KW  - telemedicine
KW  - eHealth
KW  - digital health
KW  - digital coach
KW  - weight loss
KW  - coaching
KW  - training
KW  - engagement
KW  - behavior changes
KW  - diabetes
KW  - type 2 diabetes
KW  - T2D
AB  - Background: Long-term weight loss in people living with obesity can reduce the risk and progression of noncommunicable diseases. Observational studies suggest that digital coaching can lead to long-term weight loss. Objective: We investigated whether an eHealth lifestyle coaching program for people living with obesity with or without type 2 diabetes led to significant, long-term (12-month) weight loss compared to usual care. Methods: In a randomized controlled trial that took place in 50 municipalities in Denmark, 340 people living with obesity with or without type 2 diabetes were enrolled from April 16, 2018, to April 1, 2019, and randomized via an automated computer algorithm to an intervention (n=200) or a control (n=140) group. Patients were recruited via their general practitioners, the Danish diabetes organization, and social media. The digital coaching intervention consisted of an initial 1-hour face-to-face motivational interview followed by digital coaching using behavioral change techniques enabled by individual live monitoring. The primary outcome was change in body weight from baseline to 12 months. Results: Data were assessed for 200 participants, including 127 from the intervention group and 73 from the control group, who completed 12 months of follow-up. After 12 months, mean body weight and BMI were significantly reduced in both groups but significantly more so in the intervention group than the control group (–4.5 kg, 95% CI –5.6 to –3.4 vs –1.5 kg, 95% CI –2.7 to –0.2, respectively; P<.001; and –1.5 kg/m2, 95% CI –1.9 to –1.2 vs –0.5 kg/m2, 95% CI –0.9 to –0.1, respectively; P<.001). Hemoglobin A1c was significantly reduced in both the intervention (–6.0 mmol/mol, 95% CI –7.7 to –4.3) and control (–4.9 mmol/mol, 95% CI –7.4 to –2.4) groups, without a significant group difference (all P>.46). Conclusions: Compared to usual care, digital lifestyle coaching can induce significant weight loss for people living with obesity, both with and without type 2 diabetes, after 12 months. Trial Registration: ClinicalTrials.gov NCT03788915; https://clinicaltrials.gov/ct2/show/NCT03788915 
SN  - 1438-8871
UR  - https://www.jmir.org/2022/9/e39741
UR  - https://doi.org/10.2196/39741
UR  - http://www.ncbi.nlm.nih.gov/pubmed/36149735
DO  - 10.2196/39741
ID  - info:doi/10.2196/39741
ER  -