TY - JOUR AU - Istasy, Paul AU - Lee, Wen Shen AU - Iansavichene, Alla AU - Upshur, Ross AU - Gyawali, Bishal AU - Burkell, Jacquelyn AU - Sadikovic, Bekim AU - Lazo-Langner, Alejandro AU - Chin-Yee, Benjamin PY - 2022 DA - 2022/11/1 TI - The Impact of Artificial Intelligence on Health Equity in Oncology: Scoping Review JO - J Med Internet Res SP - e39748 VL - 24 IS - 11 KW - artificial intelligence KW - eHealth KW - digital health KW - machine learning KW - oncology KW - cancer KW - health equity KW - health disparity KW - bias KW - global health KW - public health KW - cancer epidemiology KW - epidemiology KW - scoping KW - review KW - mobile phone AB - Background: The field of oncology is at the forefront of advances in artificial intelligence (AI) in health care, providing an opportunity to examine the early integration of these technologies in clinical research and patient care. Hope that AI will revolutionize health care delivery and improve clinical outcomes has been accompanied by concerns about the impact of these technologies on health equity. Objective: We aimed to conduct a scoping review of the literature to address the question, “What are the current and potential impacts of AI technologies on health equity in oncology?” Methods: Following PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews) guidelines for scoping reviews, we systematically searched MEDLINE and Embase electronic databases from January 2000 to August 2021 for records engaging with key concepts of AI, health equity, and oncology. We included all English-language articles that engaged with the 3 key concepts. Articles were analyzed qualitatively for themes pertaining to the influence of AI on health equity in oncology. Results: Of the 14,011 records, 133 (0.95%) identified from our review were included. We identified 3 general themes in the literature: the use of AI to reduce health care disparities (58/133, 43.6%), concerns surrounding AI technologies and bias (16/133, 12.1%), and the use of AI to examine biological and social determinants of health (55/133, 41.4%). A total of 3% (4/133) of articles focused on many of these themes. Conclusions: Our scoping review revealed 3 main themes on the impact of AI on health equity in oncology, which relate to AI’s ability to help address health disparities, its potential to mitigate or exacerbate bias, and its capability to help elucidate determinants of health. Gaps in the literature included a lack of discussion of ethical challenges with the application of AI technologies in low- and middle-income countries, lack of discussion of problems of bias in AI algorithms, and a lack of justification for the use of AI technologies over traditional statistical methods to address specific research questions in oncology. Our review highlights a need to address these gaps to ensure a more equitable integration of AI in cancer research and clinical practice. The limitations of our study include its exploratory nature, its focus on oncology as opposed to all health care sectors, and its analysis of solely English-language articles. SN - 1438-8871 UR - https://www.jmir.org/2022/11/e39748 UR - https://doi.org/10.2196/39748 UR - http://www.ncbi.nlm.nih.gov/pubmed/36005841 DO - 10.2196/39748 ID - info:doi/10.2196/39748 ER -