TY  - JOUR
AU  - Adly, Aya Sedky
AU  - Adly, Mahmoud Sedky
AU  - Adly, Afnan Sedky
PY  - 2021
DA  - 2021/4/28
TI  - Telemanagement of Home-Isolated COVID-19 Patients Using Oxygen Therapy With Noninvasive Positive Pressure Ventilation and Physical Therapy Techniques: Randomized Clinical Trial
JO  - J Med Internet Res
SP  - e23446
VL  - 23
IS  - 4
KW  - telemedicine
KW  - oxygen therapy
KW  - noninvasive positive airway pressure
KW  - BiPAP
KW  - osteopathic medicine
KW  - physical therapy
KW  - SARS-CoV-2
KW  - COVID-19
KW  - teletherapy
KW  - telemanagement
AB  - Background: With the growing stress on hospitals caused by the COVID-19 pandemic, the need for home-based solutions has become a necessity to support these overwhelmed hospitals. Objective: The goal of this study was to compare two nonpharmacological respiratory treatment methods for home-isolated COVID-19 patients using a newly developed telemanagement health care system. Methods: In this single-blinded randomized clinical trial, 60 patients with stage 1 pneumonia caused by SARS-CoV-2 infection were treated. Group A (n=30) received oxygen therapy with bilevel positive airway pressure (BiPAP) ventilation, and Group B (n=30) received osteopathic manipulative respiratory and physical therapy techniques. Arterial blood gases of PaO2 and PaCO2, pH, vital signs (ie, temperature, respiratory rate, oxygen saturation, heart rate, and blood pressure), and chest computed tomography scans were used for follow-up and for assessment of the course and duration of recovery. Results: Analysis of the results showed a significant difference between the two groups (P<.05), with Group A showing shorter recovery periods than Group B (mean 14.9, SD 1.7 days, and mean 23.9, SD 2.3 days, respectively). Significant differences were also observed between baseline and final readings in all of the outcome measures in both groups (P<.05). Regarding posttreatment satisfaction with our proposed telemanagement health care system, positive responses were given by most of the patients in both groups. Conclusions: It was found that home-based oxygen therapy with BiPAP can be a more effective prophylactic treatment approach than osteopathic manipulative respiratory and physical therapy techniques, as it can impede exacerbation of early-stage COVID-19 pneumonia. Telemanagement health care systems are promising methods to help in the pandemic-related shortage of hospital beds, as they showed reasonable effectiveness and reliability in the monitoring and management of patients with early-stage COVID-19 pneumonia. Trial Registration: ClinicalTrials.gov NCT04368923; https://clinicaltrials.gov/ct2/show/NCT04368923 
SN  - 1438-8871
UR  - https://www.jmir.org/2021/4/e23446
UR  - https://doi.org/10.2196/23446
UR  - http://www.ncbi.nlm.nih.gov/pubmed/33819166
DO  - 10.2196/23446
ID  - info:doi/10.2196/23446
ER  -