TY  - JOUR
AU  - Maguire, Roma
AU  - Connaghan, John
AU  - Arber, Anne
AU  - Klepacz, Naomi
AU  - Blyth, Kevin G
AU  - McPhelim, John
AU  - Murray, Paul
AU  - Rupani, Hitasha
AU  - Chauhan, Anoop
AU  - Williams, Peter
AU  - McNaughton, Laura
AU  - Woods, Kirstie
AU  - Moylan, Anne
PY  - 2020
DA  - 2020/11/12
TI  - Advanced Symptom Management System for Patients with Malignant Pleural Mesothelioma (ASyMSmeso): Mixed Methods Study
JO  - J Med Internet Res
SP  - e19180
VL  - 22
IS  - 11
KW  - malignant pleural mesothelioma
KW  - patient reported outcome measures
KW  - cancer
KW  - mobile health
KW  - telemedicine, symptom monitoring
AB  - Background: Patients with malignant pleural mesothelioma (MPM) have a life-limiting illness and short prognosis and experience many debilitating symptoms from early in the illness. Innovations such as remote symptom monitoring are needed to enable patients to maintain wellbeing and manage symptoms in a proactive and timely manner. The Advanced Symptom Management System (ASyMS) has been successfully used to monitor symptoms associated with cancer. Objective: This study aimed to determine the feasibility and acceptability of using an ASyMS adapted for use by patients with MPM, called ASyMSmeso, enabling the remote monitoring of symptoms using a smartphone. Methods: This was a convergent mixed methods study using patient-reported outcome measures (PROMs) at key time points over a period of 2-3 months with 18 patients. The Sheffield Profile for Assessment and Referral for Care (SPARC), Technology Acceptance Model (TAM) measure for eHealth, and Lung Cancer Symptom Scale-Mesothelioma (LCSS-Meso) were the PROMs used in the study. Patients were also asked to complete a daily symptom questionnaire on a smartphone throughout the study. At the end of the study, semistructured interviews with 11 health professionals, 8 patients, and 3 carers were conducted to collect their experience with using ASyMSmeso. Results: Eighteen patients with MPM agreed to participate in the study (33.3% response rate). The completion rates of study PROMs were high (97.2%-100%), and completion rates of the daily symptom questionnaire were also high, at 88.5%. There were no significant changes in quality of life, as measured by LCSS-Meso. There were statistically significant improvements in the SPARC psychological need domain (P=.049) and in the “Usefulness” domain of the TAM (P=.022). End-of-study interviews identified that both patients and clinicians found the system quick and easy to use. For patients, in particular, the system provided reassurance about symptom experience and the feeling of being listened to. The clinicians largely viewed the system as feasible and acceptable, and areas that were mentioned included the early management of symptoms and connectivity between patients and clinicians, leading to enhanced communication. Conclusions: This study demonstrates that remote monitoring and management of symptoms of people with MPM using a mobile phone are feasible and acceptable. The evidence supports future trials using remote symptom monitoring to support patients with MPM at home. 
SN  - 1438-8871
UR  - https://www.jmir.org/2020/11/e19180
UR  - https://doi.org/10.2196/19180
UR  - http://www.ncbi.nlm.nih.gov/pubmed/33180025
DO  - 10.2196/19180
ID  - info:doi/10.2196/19180
ER  -