TY  - JOUR
AU  - McManus, David D
AU  - Trinquart, Ludovic
AU  - Benjamin, Emelia J
AU  - Manders, Emily S
AU  - Fusco, Kelsey
AU  - Jung, Lindsey S
AU  - Spartano, Nicole L
AU  - Kheterpal, Vik
AU  - Nowak, Christopher
AU  - Sardana, Mayank
AU  - Murabito, Joanne M
PY  - 2019
DA  - 2019/03/01
TI  - Design and Preliminary Findings From a New Electronic Cohort Embedded in the Framingham Heart Study
JO  - J Med Internet Res
SP  - e12143
VL  - 21
IS  - 3
KW  - smartphone
KW  - tele-medicine
KW  - blood pressure monitoring
KW  - ambulatory
KW  - cohort studies
AB  - Background: New models of scalable population-based data collection that integrate digital and mobile health (mHealth) data are necessary. Objective: The aim of this study was to describe a cardiovascular digital and mHealth electronic cohort (e-cohort) embedded in a traditional longitudinal cohort study, the Framingham Heart Study (FHS). Methods: We invited eligible and consenting FHS Generation 3 and Omni participants to download the electronic Framingham Heart Study (eFHS) app onto their mobile phones and co-deployed a digital blood pressure (BP) cuff. Thereafter, participants were also offered a smartwatch (Apple Watch). Participants are invited to complete surveys through the eFHS app, to perform weekly BP measurements, and to wear the smartwatch daily. Results: Up to July 2017, we enrolled 790 eFHS participants, representing 76% (790/1044) of potentially eligible FHS participants. eFHS participants were, on average, 53±8 years of age and 57% were women. A total of 85% (675/790) of eFHS participants completed all of the baseline survey and 59% (470/790) completed the 3-month survey. A total of 42% (241/573) and 76% (306/405) of eFHS participants adhered to weekly digital BP and heart rate (HR) uploads, respectively, over 12 weeks. Conclusions: We have designed an e-cohort focused on identifying novel cardiovascular disease risk factors using a new smartphone app, a digital BP cuff, and a smartwatch. Despite minimal training and support, preliminary findings over a 3-month follow-up period show that uptake is high and adherence to periodic app-based surveys, weekly digital BP assessments, and smartwatch HR measures is acceptable. 
SN  - 1438-8871
UR  - http://www.jmir.org/2019/3/e12143/
UR  - https://doi.org/10.2196/12143
UR  - http://www.ncbi.nlm.nih.gov/pubmed/30821691
DO  - 10.2196/12143
ID  - info:doi/10.2196/12143
ER  -