%0 Journal Article
%@ 1438-8871
%I JMIR Publications
%V 26
%N 
%P e56790
%T Reporting Guidelines for the Early-Phase Clinical Evaluation of Applications Using Extended Reality: RATE-XR Qualitative Study Guideline
%A Vlake,Johan H
%A Drop,Denzel LQ
%A Van Bommel,Jasper
%A Riva,Giuseppe
%A Wiederhold,Brenda K
%A Cipresso,Pietro
%A Rizzo,Albert S
%A Rothbaum,Barbara O
%A Botella,Cristina
%A Hooft,Lotty
%A Bienvenu,Oscar J
%A Jung,Christian
%A Geerts,Bart
%A Wils,Evert-Jan
%A Gommers,Diederik
%A van Genderen,Michel E
%A ,
%+ Department of Intensive Care, Erasmus Medical Center, Doctor Molewaterplein, Rotterdam, 3015 GD, Netherlands, 31 107040704, m.vangenderen@erasmusmc.nl
%K extended reality
%K XR
%K virtual reality
%K augmented reality
%K mixed reality
%K reporting guideline
%K Delphi process
%K consensus
%K computer-generated simulation
%K simulation
%K virtual world
%K simulation experience
%K clinical evaluation
%D 2024
%7 29.11.2024
%9 Tutorial
%J J Med Internet Res
%G English
%X Background: Extended reality (XR), encompassing technologies such as virtual reality, augmented reality, and mixed reality, has rapidly gained prominence in health care. However, existing XR research often lacks rigor, proper controls, and standardization. Objective: To address this and to enhance the transparency and quality of reporting in early-phase clinical evaluations of XR applications, we present the “Reporting for the early-phase clinical evaluation of applications using extended reality” (RATE-XR) guideline. Methods: We conducted a 2-round modified Delphi process involving experts from diverse stakeholder categories, and the RATE-XR is therefore the result of a consensus-based, multistakeholder effort. Results: The guideline comprises 17 XR-specific (composed of 18 subitems) and 14 generic reporting items, each with a complementary Explanation & Elaboration section. Conclusions: The items encompass critical aspects of XR research, from clinical utility and safety to human factors and ethics. By offering a comprehensive checklist for reporting, the RATE-XR guideline facilitates robust assessment and replication of early-stage clinical XR studies. It underscores the need for transparency, patient-centeredness, and balanced evaluation of the applications of XR in health care. By providing an actionable checklist of minimal reporting items, this guideline will facilitate the responsible development and integration of XR technologies into health care and related fields. 
%R 10.2196/56790
%U https://www.jmir.org/2024/1/e56790
%U https://doi.org/10.2196/56790