%0 Journal Article
%@ 1438-8871
%I JMIR Publications
%V 26
%N 
%P e54876
%T Telehealth-Supported Exercise or Physical Activity Programs for Knee Osteoarthritis: Systematic Review and Meta-Analysis
%A Xiang,Xiao-Na
%A Wang,Ze-Zhang
%A Hu,Jing
%A Zhang,Jiang-Yin
%A Li,Ke
%A Chen,Qi-Xu
%A Xu,Fa-Shu
%A Zhang,Yue-Wen
%A He,Hong-Chen
%A He,Cheng-Qi
%A Zhu,Si-Yi
%+ Rehabilitation Medicine Center and Institute of Rehabilitation Medicine, West China Hospital, Sichuan University, No 37, Guoxue Alley, Wuhou District, Chengdu, 610041, China, 86 028 85422847, hxkfzsy@scu.edu.cn
%K telehealth
%K knee osteoarthritis
%K physical activities
%K quality of life
%K systematic review and meta-analysis
%K systematic review
%K meta-analysis
%K knee
%K physical activity
%K exercise
%K chronic disease
%K chronic disease management
%K effectiveness
%K physical function
%K self-efficacy
%D 2024
%7 2.8.2024
%9 Review
%J J Med Internet Res
%G English
%X Background: The integration of telehealth-supported programs in chronic disease management has become increasingly common. However, its effectiveness for individuals with knee osteoarthritis (KOA) remains unclear. Objective: This study aimed to assess the effectiveness of telehealth-supported exercise or physical activity programs for individuals with KOA. Methods: A comprehensive literature search encompassing Embase, MEDLINE, CENTRAL, Web of Science, PubMed, Scopus, PEDro, GreyNet, and medRxiv from inception to September 2023 was conducted to identify randomized controlled trials comparing telehealth-supported exercise or physical activity programs to a control condition for KOA. Data were extracted and qualitatively synthesized across eligible studies, and a meta-analysis was performed to evaluate the effects. The study was reported according to PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) 2020. Results: In total, 23 studies met eligibility criteria, with 20 included in the meta-analysis. Results showed that telehealth-supported exercise or physical activity programs reduced pain (g=–0.39; 95% CI –0.67 to –0.11; P<.001), improved physical activity (g=0.13; 95% CI 0.03-0.23; P=.01), and enhanced physical function (g=–0.51; 95% CI –0.98 to –0.05; P=.03). Moreover, significant improvements in quality of life (g=0.25; 95% CI 0.14-0.36; P<.001), self-efficacy for pain (g=0.72; 95% CI 0.53-0.91; P<.001), and global improvement (odds ratio 2.69, 95% CI 1.41-5.15; P<.001) were observed. However, self-efficacy for physical function (g=0.14; 95% CI –0.26 to 0.53; P=.50) showed insignificant improvements. Subgroup analyses based on the World Health Organization classification of digital health (pain: χ22=6.5; P=.04 and physical function: χ22=6.4; P=.04), the type of teletechnology in the intervention group (pain: χ24=4.8; P=.31 and function: χ24=13.0; P=.01), and active or inactive controls (pain: χ21=5.3; P=.02 and physical function: χ21=3.4; P=.07) showed significant subgroup differences. Conclusions: Telehealth-supported exercise or physical activity programs might reduce knee pain and improve physical activity, physical function, quality of life, self-efficacy, and global improvement in individuals with KOA. Future research should consider longer implementation durations and assess the feasibility of incorporating wearables and standardized components into large-scale interventions to evaluate the effects. Trial Registration: PROSPERO CRD42022359658; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=359658 
%R 10.2196/54876
%U https://www.jmir.org/2024/1/e54876
%U https://doi.org/10.2196/54876