%0 Journal Article %@ 1438-8871 %I JMIR Publications %V 26 %N %P e54678 %T Targeting Daily Positive Events to Improve Emotional and Functional Well-Being in Adults With Fibromyalgia: Insights From the LARKSPUR Randomized Controlled Trial %A Ong,Anthony %A Wilcox,Kenneth %A Reid,M Carrington %A Wethington,Elaine %A Cintron,Dakota %A Addington,Elizabeth %A Goktas,Selin %A Moskowitz,Judith %+ Department of Psychology, Cornell University, G421 Martha Van Rensselaer Hall, Cornell University, Ithaca, NY, 14850, United States, 1 6072294119, anthony.ong@cornell.edu %K positive affect %K chronic pain %K chronic condition %K long-term pain %K positive psychology %K positive events %K fibromyalgia %K mHealth %K app %K digital technology %K digital interventions %K gerontology %K geriatrics %K older adult %K aging %K well-being %D 2024 %7 10.12.2024 %9 Original Paper %J J Med Internet Res %G English %X Background: Fibromyalgia is a chronic pain condition characterized by widespread musculoskeletal pain, fatigue, and cognitive difficulties, affecting individuals across all age groups. Positive affect (PA) interventions have shown promise in enhancing emotional well-being and pain management in patients with diverse chronic pain conditions. However, the efficacy of internet-delivered PA interventions for individuals with fibromyalgia remains understudied. Objective: This randomized controlled trial investigated the efficacy of a web-based PA regulation intervention—Lessons in Affect Regulation to Keep Stress and Pain Under Control (LARKSPUR)—in enhancing emotional and functional well-being among adults with fibromyalgia syndrome. Methods: A total of 95 participants with fibromyalgia syndrome aged 50 years and older (89/95, 94% female) were randomized to one of two fully automated conditions: (1) LARKSPUR (n=49) or (2) emotion reporting/attention control (n=46). At the postintervention and 1-month follow-up time points, participants completed 7 consecutive, end-of-day, web-based reports capturing positive events (PE), pain, fatigue, PA, and negative affect. Results: Compared to control, LARKSPUR resulted in greater improvements in daily affective responsivity to PE at the postintervention time point, including greater reductions in negative affect (bL–bC=–0.06, 95% highest posterior density interval [HPD] –0.10 to –0.02) and increases in PA (bL–bC=0.10, 95% HPD 0.02-0.19). Furthermore, across the postintervention and 1-month follow-up time points, LARKSPUR led to greater reductions in pain (bL–bC=–0.20, 95% HPD –0.36 to –0.04) and fatigue (bL–bC=–0.24, 95% HPD –0.41 to –0.06) following PE. Conclusions: This randomized controlled trial provides initial evidence that a web-based PA skills intervention can enhance emotional well-being and reduce pain and fatigue in aging adults with fibromyalgia. Trial Registration: ClinicalTrials.gov NCT04869345; https://clinicaltrials.gov/study/NCT04869345 %R 10.2196/54678 %U https://www.jmir.org/2024/1/e54678 %U https://doi.org/10.2196/54678