%0 Journal Article %@ 1438-8871 %I JMIR Publications %V 25 %N %P e43123 %T Step Count, Self-reported Physical Activity, and Predicted 5-Year Risk of Atrial Fibrillation: Cross-sectional Analysis %A Shapira-Daniels,Ayelet %A Kornej,Jelena %A Spartano,Nicole L %A Wang,Xuzhi %A Zhang,Yuankai %A Pathiravasan,Chathurangi H %A Liu,Chunyu %A Trinquart,Ludovic %A Borrelli,Belinda %A McManus,David D %A Murabito,Joanne M %A Benjamin,Emelia J %A Lin,Honghuang %+ Department of Medicine, University of Massachusetts Chan Medical School, 55 North Lake Avenue, Worcester, MA, 01655, United States, 1 774 455 4881, Honghuang.Lin@umassmed.edu %K atrial fibrillation %K physical activity %K fitness tracker %K cardiovascular epidemiology %K fitness %K exercise %K tracker %K cardiology %K heart %K walk %K step count %K smartwatch %K wearable %K risk %K cross-sectional analysis %D 2023 %7 6.3.2023 %9 Original Paper %J J Med Internet Res %G English %X Background: Physical inactivity is a known risk factor for atrial fibrillation (AF). Wearable devices, such as smartwatches, present an opportunity to investigate the relation between daily step count and AF risk. Objective: The objective of this study was to investigate the association between daily step count and the predicted 5-year risk of AF. Methods: Participants from the electronic Framingham Heart Study used an Apple smartwatch. Individuals with diagnosed AF were excluded. Daily step count, watch wear time (hours and days), and self-reported physical activity data were collected. Individuals’ 5-year risk of AF was estimated, using the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE)–AF score. The relation between daily step count and predicted 5-year AF risk was examined via linear regression, adjusting for age, sex, and wear time. Secondary analyses examined effect modification by sex and obesity (BMI≥30 kg/m2), as well as the relation between self-reported physical activity and predicted 5-year AF risk. Results: We examined 923 electronic Framingham Heart Study participants (age: mean 53, SD 9 years; female: n=563, 61%) who had a median daily step count of 7227 (IQR 5699-8970). Most participants (n=823, 89.2%) had a <2.5% CHARGE-AF risk. Every 1000 steps were associated with a 0.08% lower CHARGE-AF risk (P<.001). A stronger association was observed in men and individuals with obesity. In contrast, self-reported physical activity was not associated with CHARGE-AF risk. Conclusions: Higher daily step counts were associated with a lower predicted 5-year risk of AF, and this relation was stronger in men and participants with obesity. The utility of a wearable daily step counter for AF risk reduction merits further investigation. %M 36877540 %R 10.2196/43123 %U https://www.jmir.org/2023/1/e43123 %U https://doi.org/10.2196/43123 %U http://www.ncbi.nlm.nih.gov/pubmed/36877540