%0 Journal Article
%@ 1438-8871
%I JMIR Publications
%V 24
%N 9
%P e39741
%T Long-term Weight Loss in a Primary Care–Anchored eHealth Lifestyle Coaching Program: Randomized Controlled Trial
%A Hesseldal,Laura
%A Christensen,Jeanette Reffstrup
%A Olesen,Thomas Bastholm
%A Olsen,Michael Hecht
%A Jakobsen,Pernille Ravn
%A Laursen,Ditte Hjorth
%A Lauridsen,Jørgen Trankjær
%A Nielsen,Jesper Bo
%A Søndergaard,Jens
%A Brandt,Carl Joakim
%+ Research Unit for General Practice, Department of Public Health, University of Southern Denmark, WP 9, J. B. Winsløws Vej 9A, 5000 Odense, Odense, 5000, Denmark, 45 314919945, lhesseldal@health.sdu.dk
%K obesity
%K digital behavioral coaching
%K health behavior change
%K interactive advice
%K lifestyle change
%K mobile intervention
%K patient engagement
%K telemedicine
%K eHealth
%K digital health
%K digital coach
%K weight loss
%K coaching
%K training
%K engagement
%K behavior changes
%K diabetes
%K type 2 diabetes
%K T2D
%D 2022
%7 23.9.2022
%9 Original Paper
%J J Med Internet Res
%G English
%X Background: Long-term weight loss in people living with obesity can reduce the risk and progression of noncommunicable diseases. Observational studies suggest that digital coaching can lead to long-term weight loss. Objective: We investigated whether an eHealth lifestyle coaching program for people living with obesity with or without type 2 diabetes led to significant, long-term (12-month) weight loss compared to usual care. Methods: In a randomized controlled trial that took place in 50 municipalities in Denmark, 340 people living with obesity with or without type 2 diabetes were enrolled from April 16, 2018, to April 1, 2019, and randomized via an automated computer algorithm to an intervention (n=200) or a control (n=140) group. Patients were recruited via their general practitioners, the Danish diabetes organization, and social media. The digital coaching intervention consisted of an initial 1-hour face-to-face motivational interview followed by digital coaching using behavioral change techniques enabled by individual live monitoring. The primary outcome was change in body weight from baseline to 12 months. Results: Data were assessed for 200 participants, including 127 from the intervention group and 73 from the control group, who completed 12 months of follow-up. After 12 months, mean body weight and BMI were significantly reduced in both groups but significantly more so in the intervention group than the control group (–4.5 kg, 95% CI –5.6 to –3.4 vs –1.5 kg, 95% CI –2.7 to –0.2, respectively; P<.001; and –1.5 kg/m2, 95% CI –1.9 to –1.2 vs –0.5 kg/m2, 95% CI –0.9 to –0.1, respectively; P<.001). Hemoglobin A1c was significantly reduced in both the intervention (–6.0 mmol/mol, 95% CI –7.7 to –4.3) and control (–4.9 mmol/mol, 95% CI –7.4 to –2.4) groups, without a significant group difference (all P>.46). Conclusions: Compared to usual care, digital lifestyle coaching can induce significant weight loss for people living with obesity, both with and without type 2 diabetes, after 12 months. Trial Registration: ClinicalTrials.gov NCT03788915; https://clinicaltrials.gov/ct2/show/NCT03788915 
%M 36149735
%R 10.2196/39741
%U https://www.jmir.org/2022/9/e39741
%U https://doi.org/10.2196/39741
%U http://www.ncbi.nlm.nih.gov/pubmed/36149735