%0 Journal Article %@ 1438-8871 %I JMIR Publications %V 22 %N 9 %P e22288 %T Association of Socioeconomic Changes due to the COVID-19 Pandemic With Health Outcomes in Patients With Skin Diseases: Cross-Sectional Survey Study %A Guo,Yeye %A Shen,Minxue %A Zhang,Xu %A Xiao,Yi %A Zhao,Shuang %A Yin,Mingzhu %A Bu,Wenbo %A Wang,Yan %A Chen,Xiang %A Su,Juan %+ Department of Dermatology, Xiangya Hospital, Central South University, Xiangya Road #87, Changsha, 410008, China, 86 731 84327377, sujuanderm@csu.edu.cn %K skin diseases %K coronavirus disease 2019 %K unemployment %K quality of life %K web-based %K survey %K dermatology %K COVID-19 %K lifestyle %K impact %K outcome %K isolation %D 2020 %7 11.9.2020 %9 Original Paper %J J Med Internet Res %G English %X Background: The outbreak of COVID-19 has profoundly influenced people’s lifestyles; these impacts have varied across subgroups of people. The pandemic-related impacts on the health outcomes of people with dermatological conditions are unknown. Objective: The aim of this paper was to study the association of COVID-19 pandemic–related impacts with health-related quality of life in patients with skin diseases. Methods: This was a cross-sectional study among Chinese patients with skin diseases. A self-administered web-based questionnaire was distributed through social media. Demographic and clinical data and pandemic-related impacts (isolation status, income changes, and employment status) were collected. The main outcomes included perceived stress (Visual Analog Scale), symptoms of anxiety (Generalized Anxiety Disorder-7) and depression (9-Item Patient Health Questionnaire), quality of life (Dermatology Life Quality Index), and health utility mapping based on the EQ-5D-3L descriptive system. Multivariable logistic regression was used to investigate the associations. Results: A total of 506 patients with skin diseases completed the survey. The mean age of the patients was 33.5 years (SD 14.0), and 217/506 patients (42.9%) were male. Among the 506 respondents, 128 (25.3%) were quarantined, 102 (20.2%) reported unemployment, and 317 (62.6%) reported decrease or loss of income since the pandemic. The pandemic-related impacts were significantly associated with impaired mental well-being and quality of life with different effects. Unemployment and complete loss of income were associated with the highest risks of adverse outcomes, with increases of 110% to 162% in the prevalence of anxiety, depression, and impaired quality of life. Conclusions: Isolation, income loss, and unemployment are associated with impaired health-related quality of life in patients with skin diseases during the COVID-19 pandemic. %M 32845850 %R 10.2196/22288 %U http://www.jmir.org/2020/9/e22288/ %U https://doi.org/10.2196/22288 %U http://www.ncbi.nlm.nih.gov/pubmed/32845850