%0 Journal Article %@ 1438-8871 %I JMIR Publications %V 22 %N 8 %P e21366 %T Work-Related and Personal Factors Associated With Mental Well-Being During the COVID-19 Response: Survey of Health Care and Other Workers %A Evanoff,Bradley A %A Strickland,Jaime R %A Dale,Ann Marie %A Hayibor,Lisa %A Page,Emily %A Duncan,Jennifer G %A Kannampallil,Thomas %A Gray,Diana L %+ Washington University School of Medicine, 4523 Clayton Avenue, Box 8005, St. Louis, MO, 63110, United States, 1 3144548340, bevanoff@wustl.edu %K COVID-19 %K coronavirus %K pandemic %K mental health %K health care workers %K remote work %K worker well-being %K occupational health %D 2020 %7 25.8.2020 %9 Original Paper %J J Med Internet Res %G English %X Background: The response to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has created an unprecedented disruption in work conditions. This study describes the mental health and well-being of workers both with and without clinical exposure to patients with coronavirus disease (COVID-19). Objective: The aim of this study is to measure the prevalence of stress, anxiety, depression, work exhaustion, burnout, and decreased well-being among faculty and staff at a university and academic medical center during the SARS-CoV-2 pandemic and describe work-related and personal factors associated with their mental health and well-being. Methods: All faculty, staff, and postdoctoral fellows of a university, including its medical school, were invited in April 2020 to complete an online questionnaire measuring stress, anxiety, depression, work exhaustion, burnout, and decreased well-being. We examined associations between these outcomes and factors including work in high-risk clinical settings and family/home stressors. Results: There were 5550 respondents (overall response rate of 34.3%). Overall, 34% of faculty and 14% of staff (n=915) were providing clinical care, while 61% of faculty and 77% of staff were working from home. Among all workers, anxiety (prevalence ratio 1.37, 95% CI 1.09-1.73), depression (prevalence ratio 1.28, 95% CI 1.03-1.59), and high work exhaustion (prevalence ratio 1.24, 95% CI 1.13-1.36) were independently associated with community or clinical exposure to COVID-19. Poor family-supportive behaviors by supervisors were also associated with these outcomes (prevalence ratio 1.40, 95% CI 1.21-1.62; prevalence ratio 1.69, 95% CI 1.48-1.92; and prevalence ratio 1.54, 95% CI 1.44-1.64, respectively). Age <40 years and a greater number of family/home stressors were also associated with these poorer outcomes. Among the subset of clinicians, caring for patients with COVID-19 and working in high-risk clinical settings were additional risk factors. Conclusions: Our findings suggest that the pandemic has had negative effects on the mental health and well-being of both clinical and nonclinical employees. Mitigating exposure to COVID-19 and increasing supervisor support are modifiable risk factors that may protect mental health and well-being for all workers. %M 32763891 %R 10.2196/21366 %U http://www.jmir.org/2020/8/e21366/ %U https://doi.org/10.2196/21366 %U http://www.ncbi.nlm.nih.gov/pubmed/32763891