%0 Journal Article
%@ 1438-8871
%I JMIR Publications
%V 22
%N 3
%P e18047
%T Affect-Focused Psychodynamic Internet-Based Therapy for Adolescent Depression: Randomized Controlled Trial
%A Lindqvist,Karin
%A Mechler,Jakob
%A Carlbring,Per
%A Lilliengren,Peter
%A Falkenström,Fredrik
%A Andersson,Gerhard
%A Johansson,Robert
%A Edbrooke-Childs,Julian
%A Dahl,Hanne-Sofie J
%A Lindert Bergsten,Katja
%A Midgley,Nick
%A Sandell,Rolf
%A Thorén,Agneta
%A Topooco,Naira
%A Ulberg,Randi
%A Philips,Björn
%+ Department of Psychology, Stockholm University, SE-106 91, Stockholm, Sweden, 46 (0)8 16 20 10, bjorn.philips@psychology.su.se
%K depressive disorder
%K adolescents
%K psychodynamic
%K internet-based treatment
%K treatment outcome
%K mobile phone
%D 2020
%7 30.3.2020
%9 Original Paper
%J J Med Internet Res
%G English
%X Background: Adolescent depression is one of the largest health issues in the world and there is a pressing need for effective and accessible treatments. Objective: This trial examines whether affect-focused internet-based psychodynamic therapy (IPDT) with therapist support is more effective than an internet-based supportive control condition on reducing depression in adolescents. Methods: The trial included 76 adolescents (61/76, 80% female; mean age 16.6 years), self-referred via an open access website and fulfilling criteria for major depressive disorder. Adolescents were randomized to 8 weeks of IPDT (38/76, 50%) or supportive control (38/76, 50%). The primary outcome was self-reported depressive symptoms, measured with the Quick Inventory of Depressive Symptomatology for Adolescents (QIDS-A17-SR). Secondary outcomes were anxiety severity, emotion regulation, self-compassion, and an additional depression measure. Assessments were made at baseline, postassessment, and at 6 months follow-up, in addition to weekly assessments of the primary outcome measure as well as emotion regulation during treatment. Results: IPDT was significantly more effective than the control condition in reducing depression (d=0.82, P=.01), the result of which was corroborated by the second depression measure (d=0.80, P<.001). IPDT was also significantly more effective in reducing anxiety (d=0.78, P<.001) and increasing emotion regulation (d=0.97, P<.001) and self-compassion (d=0.65, P=.003). Significantly more patients in the IPDT group compared to the control group met criteria for response (56% vs 21%, respectively) and remission (35% vs 8%, respectively). Results on depression and anxiety symptoms were stable at 6 months follow-up. On average, participants completed 5.8 (SD 2.4) of the 8 modules. Conclusions: IPDT may be an effective intervention to reduce adolescent depression. Further research is needed, including comparisons with other treatments. Trial Registration: International Standard Randomised Controlled Trial Number (ISRCTN) 16206254; http://www.isrctn.com/ISRCTN16206254 
%M 32224489
%R 10.2196/18047
%U http://www.jmir.org/2020/3/e18047/
%U https://doi.org/10.2196/18047
%U http://www.ncbi.nlm.nih.gov/pubmed/32224489