%0 Journal Article %@ 1438-8871 %I JMIR Publications %V 19 %N 3 %P e76 %T The Effect of Technology-Mediated Diabetes Prevention Interventions on Weight: A Meta-Analysis %A Bian,Rachel R %A Piatt,Gretchen A %A Sen,Ananda %A Plegue,Melissa A %A De Michele,Mariana L %A Hafez,Dina %A Czuhajewski,Christina M %A Buis,Lorraine R %A Kaufman,Neal %A Richardson,Caroline R %+ University of Michigan, Department of Family Medicine, 1018 Fuller St., Ann Arbor, MI, 48104, United States, 1 734 998 7120, caroli@umich.edu %K diabetes mellitus, type 2 %K weight reduction programs %K technology %K meta-analysis %K prediabetic state %D 2017 %7 27.03.2017 %9 Original Paper %J J Med Internet Res %G English %X Background: Lifestyle interventions targeting weight loss, such as those delivered through the Diabetes Prevention Program, reduce the risk of developing type 2 diabetes. Technology-mediated interventions may be an option to help overcome barriers to program delivery, and to disseminate diabetes prevention programs on a larger scale. Objective: We conducted a meta-analysis to evaluate the effect of such technology-mediated interventions on weight loss. Methods: In this meta-analysis, six databases were searched to identify studies reporting weight change that used technology to mediate diet and exercise interventions, and targeted individuals at high risk for developing type 2 diabetes. Studies published between January 1, 2002 and August 4, 2016 were included. Results: The search identified 1196 citations. Of those, 15 studies met the inclusion criteria and evaluated 18 technology-mediated intervention arms delivered to a total of 2774 participants. Study duration ranged from 12 weeks to 2 years. A random-effects meta-analysis showed a pooled weight loss effect of 3.76 kilograms (95% CI 2.8-4.7; P<.001) for the interventions. Several studies also reported improved glycemic control following the intervention. The small sample sizes and heterogeneity of the trials precluded an evaluation of which technology-mediated intervention method was most efficacious. Conclusions: Technology-mediated diabetes prevention programs can result in clinically significant amounts of weight loss, as well as improvements in glycaemia in patients with prediabetes. Due to their potential for large-scale implementation, these interventions will play an important role in the dissemination of diabetes prevention programs. %M 28347972 %R 10.2196/jmir.4709 %U http://www.jmir.org/2017/3/e76/ %U https://doi.org/10.2196/jmir.4709 %U http://www.ncbi.nlm.nih.gov/pubmed/28347972