%0 Journal Article %@ 14388871 %I JMIR Publications Inc. %V 16 %N 3 %P e82 %T Efficacy of a Web-Based Computer-Tailored Smoking Prevention Intervention for Dutch Adolescents: Randomized Controlled Trial %A de Josselin de Jong,Sanne %A Candel,Math %A Segaar,Dewi %A Cremers,Henricus-Paul %A de Vries,Hein %+ Trimbos Institute (Netherlands Institute of Mental Health and Addiction), Da Costakade 45, PO Box 725, Utrecht, 3500 AS, Netherlands, 31 30 295 9239, sdejosselindejong@trimbos.nl %K computer tailoring %K Web-based intervention %K Internet %K smoking prevention %K smoking initiation %K adolescents %K randomized controlled trial %D 2014 %7 21.03.2014 %9 Original Paper %J J Med Internet Res %G English %X Background: Preventing smoking initiation among adolescents is crucial to reducing tobacco-caused death and disease. This study focuses on the effectiveness of a Web-based computer-tailored smoking prevention intervention aimed at adolescents. Objective: The intent of the study was to describe the intervention characteristics and to show the effectiveness and results of a randomized controlled trial. We hypothesized that the intervention would prevent smoking initiation among Dutch secondary school students aged 10-20 years and would have the largest smoking prevention effect among the age cohort of 14-16 years, as smoking uptake in that period is highest. Methods: The intervention consisted of a questionnaire and fully automated computer-tailored feedback on intention to start smoking and motivational determinants. A total of 89 secondary schools were recruited via postal mail and randomized into either the computer-tailored intervention condition or the control condition. Participants had to complete a Web-based questionnaire at baseline and at 6-month follow-up. Data on smoking initiation were collected from 897 students from these schools. To identify intervention effects, multilevel logistic regression analyses were conducted using multiple imputation. Results: Smoking initiation among students aged 10-20 years was borderline significantly lower in the experimental condition as compared to the control condition 6 months after baseline (OR 0.25, 95% CI 0.05-1.21, P=.09). Additional analyses of the data for the 14-16 year age group showed a significant effect, with 11.5% (24/209) of the students in the control condition reporting initiation compared to 5.7% (10/176) in the experimental condition (OR 0.22, 95% CI 0.05-1.02, P=.05). No moderation effects were found regarding gender and educational level. Conclusions: The findings of this study suggest that computer-tailored smoking prevention programs are a promising way of preventing smoking initiation among adolescents for at least 6 months, in particular among the age cohort of 14-16 years. Further research is needed to focus on long-term effects. Trial Registration: International Standard Randomized Controlled Trial Number (ISRCTN): 77864351; http://www.controlled-trials.com/ISRCTN77864351 (Archived by WebCite at http://www.webcitation.org/6BSLKSTm5). %M 24657434 %R 10.2196/jmir.2469 %U http://www.jmir.org/2014/3/e82/ %U https://doi.org/10.2196/jmir.2469 %U http://www.ncbi.nlm.nih.gov/pubmed/24657434