@Article{info:doi/10.2196/54678, author="Ong, Anthony and Wilcox, Kenneth and Reid, M Carrington and Wethington, Elaine and Cintron, Dakota and Addington, Elizabeth and Goktas, Selin and Moskowitz, Judith", title="Targeting Daily Positive Events to Improve Emotional and Functional Well-Being in Adults With Fibromyalgia: Insights From the LARKSPUR Randomized Controlled Trial", journal="J Med Internet Res", year="2024", month="Dec", day="10", volume="26", pages="e54678", keywords="positive affect; chronic pain; chronic condition; long-term pain; positive psychology; positive events; fibromyalgia; mHealth; app; digital technology; digital interventions; gerontology; geriatrics; older adult; aging; well-being", abstract="Background: Fibromyalgia is a chronic pain condition characterized by widespread musculoskeletal pain, fatigue, and cognitive difficulties, affecting individuals across all age groups. Positive affect (PA) interventions have shown promise in enhancing emotional well-being and pain management in patients with diverse chronic pain conditions. However, the efficacy of internet-delivered PA interventions for individuals with fibromyalgia remains understudied. Objective: This randomized controlled trial investigated the efficacy of a web-based PA regulation intervention---Lessons in Affect Regulation to Keep Stress and Pain Under Control (LARKSPUR)---in enhancing emotional and functional well-being among adults with fibromyalgia syndrome. Methods: A total of 95 participants with fibromyalgia syndrome aged 50 years and older (89/95, 94{\%} female) were randomized to one of two fully automated conditions: (1) LARKSPUR (n=49) or (2) emotion reporting/attention control (n=46). At the postintervention and 1-month follow-up time points, participants completed 7 consecutive, end-of-day, web-based reports capturing positive events (PE), pain, fatigue, PA, and negative affect. Results: Compared to control, LARKSPUR resulted in greater improvements in daily affective responsivity to PE at the postintervention time point, including greater reductions in negative affect (bL--bC=--0.06, 95{\%} highest posterior density interval [HPD] --0.10 to --0.02) and increases in PA (bL--bC=0.10, 95{\%} HPD 0.02-0.19). Furthermore, across the postintervention and 1-month follow-up time points, LARKSPUR led to greater reductions in pain (bL--bC=--0.20, 95{\%} HPD --0.36 to --0.04) and fatigue (bL--bC=--0.24, 95{\%} HPD --0.41 to --0.06) following PE. Conclusions: This randomized controlled trial provides initial evidence that a web-based PA skills intervention can enhance emotional well-being and reduce pain and fatigue in aging adults with fibromyalgia. Trial Registration: ClinicalTrials.gov NCT04869345; https://clinicaltrials.gov/study/NCT04869345 ", issn="1438-8871", doi="10.2196/54678", url="https://www.jmir.org/2024/1/e54678", url="https://doi.org/10.2196/54678" }