@Article{info:doi/10.2196/22288, author="Guo, Yeye and Shen, Minxue and Zhang, Xu and Xiao, Yi and Zhao, Shuang and Yin, Mingzhu and Bu, Wenbo and Wang, Yan and Chen, Xiang and Su, Juan", title="Association of Socioeconomic Changes due to the COVID-19 Pandemic With Health Outcomes in Patients With Skin Diseases: Cross-Sectional Survey Study", journal="J Med Internet Res", year="2020", month="Sep", day="11", volume="22", number="9", pages="e22288", keywords="skin diseases; coronavirus disease 2019; unemployment; quality of life; web-based; survey; dermatology; COVID-19; lifestyle; impact; outcome; isolation", abstract="Background: The outbreak of COVID-19 has profoundly influenced people's lifestyles; these impacts have varied across subgroups of people. The pandemic-related impacts on the health outcomes of people with dermatological conditions are unknown. Objective: The aim of this paper was to study the association of COVID-19 pandemic--related impacts with health-related quality of life in patients with skin diseases. Methods: This was a cross-sectional study among Chinese patients with skin diseases. A self-administered web-based questionnaire was distributed through social media. Demographic and clinical data and pandemic-related impacts (isolation status, income changes, and employment status) were collected. The main outcomes included perceived stress (Visual Analog Scale), symptoms of anxiety (Generalized Anxiety Disorder-7) and depression (9-Item Patient Health Questionnaire), quality of life (Dermatology Life Quality Index), and health utility mapping based on the EQ-5D-3L descriptive system. Multivariable logistic regression was used to investigate the associations. Results: A total of 506 patients with skin diseases completed the survey. The mean age of the patients was 33.5 years (SD 14.0), and 217/506 patients (42.9{\%}) were male. Among the 506 respondents, 128 (25.3{\%}) were quarantined, 102 (20.2{\%}) reported unemployment, and 317 (62.6{\%}) reported decrease or loss of income since the pandemic. The pandemic-related impacts were significantly associated with impaired mental well-being and quality of life with different effects. Unemployment and complete loss of income were associated with the highest risks of adverse outcomes, with increases of 110{\%} to 162{\%} in the prevalence of anxiety, depression, and impaired quality of life. Conclusions: Isolation, income loss, and unemployment are associated with impaired health-related quality of life in patients with skin diseases during the COVID-19 pandemic. ", issn="1438-8871", doi="10.2196/22288", url="http://www.jmir.org/2020/9/e22288/", url="https://doi.org/10.2196/22288", url="http://www.ncbi.nlm.nih.gov/pubmed/32845850" }