@Article{info:doi/10.2196/12143,
author="McManus, David D
and Trinquart, Ludovic
and Benjamin, Emelia J
and Manders, Emily S
and Fusco, Kelsey
and Jung, Lindsey S
and Spartano, Nicole L
and Kheterpal, Vik
and Nowak, Christopher
and Sardana, Mayank
and Murabito, Joanne M",
title="Design and Preliminary Findings From a New Electronic Cohort Embedded in the Framingham Heart Study",
journal="J Med Internet Res",
year="2019",
month="Mar",
day="01",
volume="21",
number="3",
pages="e12143",
keywords="smartphone; tele-medicine; blood pressure monitoring; ambulatory; cohort studies",
abstract="Background: New models of scalable population-based data collection that integrate digital and mobile health (mHealth) data are necessary. Objective: The aim of this study was to describe a cardiovascular digital and mHealth electronic cohort (e-cohort) embedded in a traditional longitudinal cohort study, the Framingham Heart Study (FHS). Methods: We invited eligible and consenting FHS Generation 3 and Omni participants to download the electronic Framingham Heart Study (eFHS) app onto their mobile phones and co-deployed a digital blood pressure (BP) cuff. Thereafter, participants were also offered a smartwatch (Apple Watch). Participants are invited to complete surveys through the eFHS app, to perform weekly BP measurements, and to wear the smartwatch daily. Results: Up to July 2017, we enrolled 790 eFHS participants, representing 76{\%} (790/1044) of potentially eligible FHS participants. eFHS participants were, on average, 53{\textpm}8 years of age and 57{\%} were women. A total of 85{\%} (675/790) of eFHS participants completed all of the baseline survey and 59{\%} (470/790) completed the 3-month survey. A total of 42{\%} (241/573) and 76{\%} (306/405) of eFHS participants adhered to weekly digital BP and heart rate (HR) uploads, respectively, over 12 weeks. Conclusions: We have designed an e-cohort focused on identifying novel cardiovascular disease risk factors using a new smartphone app, a digital BP cuff, and a smartwatch. Despite minimal training and support, preliminary findings over a 3-month follow-up period show that uptake is high and adherence to periodic app-based surveys, weekly digital BP assessments, and smartwatch HR measures is acceptable. ",
issn="1438-8871",
doi="10.2196/12143",
url="http://www.jmir.org/2019/3/e12143/",
url="https://doi.org/10.2196/12143",
url="http://www.ncbi.nlm.nih.gov/pubmed/30821691"
}