@Article{info:doi/10.2196/jmir.4709, author="Bian, Rachel R and Piatt, Gretchen A and Sen, Ananda and Plegue, Melissa A and De Michele, Mariana L and Hafez, Dina and Czuhajewski, Christina M and Buis, Lorraine R and Kaufman, Neal and Richardson, Caroline R", title="The Effect of Technology-Mediated Diabetes Prevention Interventions on Weight: A Meta-Analysis", journal="J Med Internet Res", year="2017", month="Mar", day="27", volume="19", number="3", pages="e76", keywords="diabetes mellitus, type 2; weight reduction programs; technology; meta-analysis; prediabetic state", abstract="Background: Lifestyle interventions targeting weight loss, such as those delivered through the Diabetes Prevention Program, reduce the risk of developing type 2 diabetes. Technology-mediated interventions may be an option to help overcome barriers to program delivery, and to disseminate diabetes prevention programs on a larger scale. Objective: We conducted a meta-analysis to evaluate the effect of such technology-mediated interventions on weight loss. Methods: In this meta-analysis, six databases were searched to identify studies reporting weight change that used technology to mediate diet and exercise interventions, and targeted individuals at high risk for developing type 2 diabetes. Studies published between January 1, 2002 and August 4, 2016 were included. Results: The search identified 1196 citations. Of those, 15 studies met the inclusion criteria and evaluated 18 technology-mediated intervention arms delivered to a total of 2774 participants. Study duration ranged from 12 weeks to 2 years. A random-effects meta-analysis showed a pooled weight loss effect of 3.76 kilograms (95{\%} CI 2.8-4.7; P<.001) for the interventions. Several studies also reported improved glycemic control following the intervention. The small sample sizes and heterogeneity of the trials precluded an evaluation of which technology-mediated intervention method was most efficacious. Conclusions: Technology-mediated diabetes prevention programs can result in clinically significant amounts of weight loss, as well as improvements in glycaemia in patients with prediabetes. Due to their potential for large-scale implementation, these interventions will play an important role in the dissemination of diabetes prevention programs. ", issn="1438-8871", doi="10.2196/jmir.4709", url="http://www.jmir.org/2017/3/e76/", url="https://doi.org/10.2196/jmir.4709", url="http://www.ncbi.nlm.nih.gov/pubmed/28347972" }