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Web-based and Mobile Health Interventions (3297)

Published on in Vol 18, No 5 (2016): May

The Effectiveness of a Web-Based Computer-Tailored Intervention on Workplace Sitting: A Randomized Controlled Trial

The Effectiveness of a Web-Based Computer-Tailored Intervention on Workplace Sitting: A Randomized Controlled Trial

The Effectiveness of a Web-Based Computer-Tailored Intervention on Workplace Sitting: A Randomized Controlled Trial

Authors of this article:

Katrien De Cocker1, 2 Author Orcid Image ;   Ilse De Bourdeaudhuij1 Author Orcid Image ;   Greet Cardon1 Author Orcid Image ;   Corneel Vandelanotte3 Author Orcid Image
Article Authors Cited by (41) Tweetations (11) Metrics

    Original Paper

    1Department of Movement and Sports Sciences, Ghent University, Ghent, Belgium

    2Research Foundation Flanders, Brussels, Belgium

    3Physical Activity Research Group, School for Human Health and Social Sciences, Central Queensland University, Rockhampton, Australia

    Corresponding Author:

    Katrien De Cocker, PhD

    Department of Movement and Sports Sciences

    Ghent University

    Watersportlaan 2

    Ghent, 9000

    Belgium

    Phone: 32 264 63 23

    Fax:32 264 84 64

    Email: Katrien.DeCocker@ugent.be


    Background: Effective interventions to influence workplace sitting are needed, as office-based workers demonstrate high levels of continued sitting, and sitting too much is associated with adverse health effects. Therefore, we developed a theory-driven, Web-based, interactive, computer-tailored intervention aimed at reducing and interrupting sitting at work.

    Objective: The objective of our study was to investigate the effects of this intervention on objectively measured sitting time, standing time, and breaks from sitting, as well as self-reported context-specific sitting among Flemish employees in a field-based approach.

    Methods: Employees (n=213) participated in a 3-group randomized controlled trial that assessed outcomes at baseline, 1-month follow-up, and 3-month follow-up through self-reports. A subsample (n=122) were willing to wear an activity monitor (activPAL) from Monday to Friday. The tailored group received an automated Web-based, computer-tailored intervention including personalized feedback and tips on how to reduce or interrupt workplace sitting. The generic group received an automated Web-based generic advice with tips. The control group was a wait-list control condition, initially receiving no intervention. Intervention effects were tested with repeated-measures multivariate analysis of variance.

    Results: The tailored intervention was successful in decreasing self-reported total workday sitting (time × group: P<.001), sitting at work (time × group: P<.001), and leisure time sitting (time × group: P=.03), and in increasing objectively measured breaks at work (time × group: P=.07); this was not the case in the other conditions. The changes in self-reported total nonworkday sitting, sitting during transport, television viewing, and personal computer use, objectively measured total sitting time, and sitting and standing time at work did not differ between conditions.

    Conclusions: Our results point out the significance of computer tailoring for sedentary behavior and its potential use in public health promotion, as the effects of the tailored condition were superior to the generic and control conditions.

    Trial Registration: Clinicaltrials.gov NCT02672215; http://clinicaltrials.gov/ct2/show/NCT02672215 (Archived by WebCite at http://www.webcitation.org/6glPFBLWv)

    J Med Internet Res 2016;18(5):e96

    doi:10.2196/jmir.5266

    Keywords

    sedentary behavior; computer tailoring; employees; activPAL; sitting time; randomized controlled trial 


    In modern societies, adults spend the majority of their waking time in sedentary behaviors, that is, activities in a sitting or reclining posture characterized by a low energy expenditure [1]. Working hours are probably the largest contributor to overall daily sitting time in adults. Flemish and Australian employees spent, respectively, about 71% and 77% of their working hours being sedentary [2-4]. Increasing evidence suggests that too much sitting is related to adverse health outcomes, independent of physical activity levels [5,6]. Both the total amount of sitting and the pattern of sitting (ie, prolonged uninterrupted periods) are associated with several adverse health effects in adults, such as obesity, metabolic syndrome, type 2 diabetes mellitus, some cancers, and all-cause and cardiovascular disease mortality [5-8]. Therefore, interventions to reduce (limit the amount of sitting) or interrupt (limit prolonged sitting bouts) sitting at work are warranted [9].

    The evidence regarding the effectiveness of workplace interventions focusing on occupational sitting is growing [10,11]. Current workplace interventions are single- or multicomponent programs implementing individual or environmental strategies to influence workplace sitting. Examples of individual strategies are face-to-face behavioral change counselling sessions [12], workplace information sessions [13,14], tailored support for individual behavioral change through goal setting [13,14], and motivational interviewing [13,14]. Environmental strategies include the introduction of sit-stand workstations [15-17], portable pedal machines [18], and prompting software reminders [19,20]. Effects of these strategies are promising, with reductions in (mostly objectively measured) workplace sitting time (ranging from -28 to -262 minutes/8-hour workday) [12-14,18], and fewer (-4.6 bouts) and shorter (-5.6 minutes) sitting bouts [13].

    A review of sit-stand workstations suggests that they can be effective in reducing occupational sitting time (the pooled effect size of 7 intervention studies was -77 minutes of sitting/8-hour workday), without compromising work performance [21]. However, these types of environmental interventions may not be feasible due to their high initial costs [22]. As a result, alternative interventions targeting workplace sitting are needed [9] in order to find out which other strategies are effective. In addition, most of the previous effectiveness studies were conducted in relatively small (maximum 62 participants) samples of employees or by low-quality evaluation methods [23]. This suggests that workplace intervention studies in larger samples are needed to increase our understanding of effective strategies to influence workplace sitting.

    One popular public health promotion method that has been shown to successfully change a variety of health-related behaviors (dietary behaviors, alcohol consumption, smoking habits, and physical activity) is Web-based computer tailoring [24-26]. Computer-tailored interventions require participants to complete 1 or more brief assessment surveys. Then, based on participants’ answers, a computer program selects the relevant feedback messages from a database (through if-then algorithms), with the intention to provide information that is as personally relevant as possible [26]. Delivered thought the Internet, this approach has several advantages, including low cost, no limitations due to time or location, and a large reach, as the Internet now has 2 billion users worldwide [27]. In addition, interactive Web-based interventions have several benefits. First, they create the opportunity for ongoing contact with, and support to, their users [28,29]. Second, they apply tools that support self-regulatory skills, such as goal-setting activities, self-monitoring tools, action planning, skill-building activities, email reminders, and booster sessions [28,29]. To our knowledge, no workplace interventions targeting sitting have examined the effectiveness of Web-based computer-tailored program, and it seems worthwhile to investigate the effects of this type of workplace interventions.

    We developed a theory-driven, Web-based, computer-tailored intervention to influence sitting at work and found it to be acceptable in terms of the assessment questioning, interestingness, length, credibility, and relevance of the advice [30]. In this study, we aimed to investigate the effects of this computer-tailored intervention to influence workplace sitting [30] on objectively measured sitting time, standing time, and breaks from sitting, as well as self-reported context-specific sitting. We compared the computer-tailored advice with generic advice and a no-advice control at 1-month and 3-month follow-ups. We hypothesized that both interventions would result in beneficial changes compared with the control condition, but that the effects of the computer-tailored advice would be significantly greater than the effects of generic advice.


    Study Design and Sample

    The study used a controlled baseline (T0), 1-month follow-up (T1), and 3-month follow-up (T2: T0+3 months) design, with 3 different conditions (Figure 1 provides the study flow chart). The tailored group received a Web-based, computer-tailored intervention including personalized feedback and tips on reducing or interrupting workplace sitting (see the Interventions subsection below). The generic group received a Web-based intervention containing generic information and tips on reducing or interrupting workplace sitting. The control group was a wait-list control condition and received the generic intervention after completing all measurements.

    We selected a convenience sample of 2 companies (a university and an environmental agency) in Flanders (ie, the northern, Dutch-speaking part of Belgium), mainly employing desk-based workers, having more than 100 staff members, and each having at least three different worksite locations. Both workplaces had a general health policy following European legislations and were informally committed to health aspects, but they did not yet focus on healthy sedentary behavior at work. We contacted company management by phone and email to inform them about the study, and both companies agreed to participate in this study (response rate 100%). Within the university, 3 departments of the central administration were selected to participate, and within the environmental agency, 3 departments in East Flanders were selected. Within each company, each department was randomly assigned to 1 of the 3 conditions. All selected departments were in different physical locations and the employees had little face-to-face contact with one another, reducing the opportunity for contamination between groups.

    ‎
    Figure 1. Flow chart of a randomized controlled trial of an intervention to reduce and interrupt sitting time at work.
    View this figure

    Procedures

    A contact person in each department provided the email addresses of all employees. In October 2014, employees were invited to participate by email. Employees willing to participate were asked to reply to the email within 1 week, indicating whether they wanted to complete the Web-based questionnaires only or whether they wanted to complete the Web-based questionnaires and additionally wear an activity monitor. We sent a reminder email with the invitation to those who had not yet responded, 1 day before the enrollment deadline. The study protocols were approved by the Ethics Committee of the Ghent University Hospital, Belgium.

    A researcher emailed a confidential website username and password to all participants. After logging in, participants received a short introduction pop-up screen and were then referred to the home page, inviting them to complete an assessment questionnaire (see the Measures subsection below). After completing the baseline questionnaire, each group received different feedback. Those who were interested in participating but who did not complete the questionnaire within 7 days were sent up to 3 automatic reminders to visit the website.

    A member of the research team visited the participants willing to wear an activity monitor at their workplace on a Monday. They were instructed to wear the monitor on the thigh from Monday to Friday. A researcher covered the monitor with a transparent medical tape (Tegaderm, 3M, Diegem, Belgium) before placement, and also attached the monitor itself with this tape. These waterproof attachments allowed for 24-hour wear, including water activities (eg, bathing and swimming). Monitor data from 3 days (Tuesday, Wednesday, and Thursday) were used for this study [31]. During the 3 full days of data collection, participants were also requested to complete a day log. On Friday, the researcher recollected the monitors at the workplace. These procedures were repeated at the 3 time points (T0, T1, and T2). The study was conducted between October 2014 and March 2015.

    Interventions

    Computer Tailored Intervention

    The development of this theory-driven intervention, called Start to Stand, has been described in detail elsewhere [30]. In brief, in this Web-based intervention, after completing an assessment questionnaire, users received personalized computer-tailored feedback about their sitting time, including tips and suggestions on how to interrupt (taking short standing breaks) and reduce (replacing sitting by periods of standing) sitting. Several questions on the Web-based questionnaire (see the Measures subsection below) were used to build up the feedback. The information requested from the participants referred to job-related information, knowledge about sedentary behavior, level of sitting time in 5 domains, frequency of interruptions in prolonged sitting, and level of physical activity. A set of decision rules selected the feedback messages that were matched and tailored to the specific answers given by the users. The combination of these feedback messages formed the tailored advice that appeared immediately on the user’s screen. We took into account constructs of the self-determination theory [32], the theory of planned behavior [33], and self-regulation theory [34]. Web-based interventions that use theory are more likely to have positive effects than those that are not theory based [35]. Interventions tailored to 4 or 5 theoretical concepts, such as social support, self-efficacy, and stages of change, were found to be more positive than interventions tailored to fewer than 3 theoretical concepts [36].

    To increase their knowledge, participants first received general information about the importance of sitting behavior to improve health outcomes. This was followed by normative feedback about their own sitting behavior on working and nonworking days, in order to increase awareness of participants’ levels of sitting time. Further, feedback on the frequency of breaks from sitting, information on the importance of these breaks for health, and the suggestion to interrupt prolonged sitting every 30 minutes was provided [14,37]. Also the negative health impact of too much sitting, independent of physical activity levels, was explained. Next, feedback on participants’ physical activity level was given (see [30] for details).

    At the end of this advice (section 1), participants were able to request up to 5 other noncommittal sections if they were interested. In line with the self-determination theory [32], users were able to choose which section of the advice they wanted to request additionally, instead of forcing users to complete all assessment questions at once and providing extensive advice containing all information. Leaving a choice for the users is assumed to increase autonomous motivation, which is more likely to lead to behavioral change [32]. The focus of these additional sections was on sitting during work hours (section 2: standing breaks; section 3: replacing sitting by standing), sitting during commuting to work (section 4), sitting during lunch breaks at work (section 5); and on making an action plan to improve sitting behavior (section 6). For each section, a brief questionnaire assessed participants’ current sitting behaviors and related psychosocial correlates (attitudes, self-efficacy, social support, intentions, and perceived benefits and barriers) [30]. Throughout the advice, the tailoring constructs were based on the theory of planned behavior [32], a theory focusing on the intention (or motivation) to adopt or modify a behavior and assuming that the intention is higher when people have more positive attitudes, perceived social influence, and self-efficacy. After participants completed each assessment questionnaire, the tailored advice appeared immediately on the computer screen. Participants were given personalized feedback about their attitudes, self-efficacy, social support, knowledge, intentions, and perceived benefits and barriers related to reducing or interrupting sitting.

    In the last section, participants who were motivated to change their sitting were invited to create an action plan to convert intentions into specific actions through the specific, measurable, attainable, relevant, and time-bound (SMART) goals and implementation intentions [34,38], as goal setting has been found to be a common and effective intervention technique used in other health behavioral change programs. The action plan operates within the self-regulation theory, targeting pre- and postintentional processes to guide behavioral change [34]. Users were asked what (increase standing breaks, or replace sitting by standing, or both) they wanted to do, how long, how often, when, and how in order to state personally relevant and attainable goals. Finally, users were able to select precomposed if-then statements to make an if-then plan. Users were also able to formulate if-then statements themselves in an open-ended question format. When these questions were completed, a schematic overview of this personalized action plan was immediately provided on the screen [30].

    Some screenshots of the tool are provided in Multimedia Appendix 1.

    Generic Intervention

    In the generic advice condition, after completing the baseline assessment questionnaire, users received generic information on the importance of reducing and interrupting sitting, and generic tips and suggestions on how to interrupt (taking short standing breaks, 6 tips) and reduce (replacing sitting by periods of standing, 8 tips) sitting during work hours, (lunch) breaks, and commuting (topics similar to the tailored group). While the information covered the same topics as in the tailored group, the generic group didn’t receive personalized advice or an action plan, and all information appeared on a single screen page.

    Measures

    Web-Based Questionnaire

    The questionnaire consisted of several parts, and all questions were asked at T0, T1, and T2, except for unchangeable variables, such as height.

    Sociodemographics

    The following sociodemographic variables were assessed: sex, age, highest educational degree with 5 options dichotomized into low (no diploma, elementary school, secondary school) and high (high school, university) education, height, and weight.

    Work-Related Variables

    We asked about the number of workdays per week (1–7), average daily amount of time (hours and minutes) spent at the workplace (open-ended), occupational status (blue collar, white collar, management), and employment duration (14 categories ranging from 1–6 months to 55–60 years).

    Self-reported Behavioral Measures

    We assessed the level of sitting time in 5 domains using the Workforce Sitting Questionnaire (WSQ) [39]. This questionnaire assessed time spent sitting on a workday and a nonworkday for the last 7 days while (1) travelling to and from places, (2) being at work, (3) watching television, (4) using a computer at home (not work related), and (5) doing other leisure activities. The WSQ has acceptable reliability (interclass correlation coefficient=.63) and validity against objectively accelerometer-measured sitting time (r=.34 to r=.45) [39]. Participants were also asked to report the average number of breaks from sitting they have on a regular workday [40].

    The validated International Physical Activity Questionnaire (IPAQ) short version [41,42] assessed the number of days and duration of time spent in walking, moderate-intensity physical activity, and vigorous-intensity physical activity in the preceding week.

    Activity Monitor and Day Log

    Sedentary behavior was measured objectively using the activPAL (PAL Technologies, Glasgow, UK) activity monitor (weight 15 g, dimensions 53 × 35 × 7 mm). This inclinometer, distinguishing periods of sitting or lying from standing and assessing breaks from sitting, has been validated (correlation between activPAL and direct observation: R2=.94) in adults [43] and was recommended to assess sedentary behavior [43,44].

    Participants were requested to complete a day log and record the type of day (workday at home, workday at the workplace, or nonworkday), time of getting up, the start and end time of the working day, and the time of going to sleep.

    Website Usage Statistics

    We collected the number of participants requesting the different sections of the advice from the website administration. Google Analytics provided data on website visiting time [45].

    Data Reduction

    Data recorded by activPAL were reduced using PAL Technologies software (version 6.4.1). We calculated waking sitting time by subtracting sleep time reported in the day log from the total sitting time recorded by the activPAL device. The percentage of working time spent sitting was calculated as sitting time during work hours/work hours × 100. We used similar formulas to calculate percentage of working time spent standing and number of breaks per working hour. We calculated average values for T0, T1, and T2 from the mean scores of the 3 measurement days.

    Within the 5 domains assessed using the WSQ, we truncated values over 12 hours/day to 12 hours to avoid unrealistic values [30]. We calculated total time spent sitting on a workday and on a nonworkday by summing the time reported in every domain. These totals were truncated at 16 hours/day [30].

    Based on the guidelines for data processing and analysis of the IPAQ [46], total scores for walking, and moderate and vigorous physical activities were computed (number of days × time duration). Body mass index (BMI) was calculated as weight in kg divided by height in m2.

    Data Analyses

    All analyses were conducted in SPSS version 22.0 (IBM Corporation) and significance was set at P<.05, while P values between .05 and .10 were interpreted as indicating borderline significance. We did not perform any multilevel analyses because there were fewer than 10 clusters and none of the variables were measured at cluster level [47]. The 3 groups’ characteristics at baseline were compared using 1-way analysis of variance (for the quantitative variables age and BMI) or χ2 tests (for the qualitative variables sex, education, work regimen, occupational status, and employment duration). We conducted the same analyses to compare the characteristics of participants willing to wear the activity monitor at baseline and those not willing to wear it. Descriptive statistics for usage of the various website components are provided.

    To investigate the 1-month and 3-month follow-up effects of the intervention, we conducted 3 repeated-measures multivariate analysis of variance tests with time (T0, T1, or T2) as the within-participants factor, condition (3 groups) as the between-participants factor, and self-reported sitting (workday and nonworkday total sitting; average daily domain-specific sitting) and objectively measured sitting (total waking sitting time, working time spent sitting, working time spent standing, breaks from sitting per work hour) as the dependent variables. When the time (3 levels) × condition (3 levels) effects were significant, we conducted additional post hoc repeated-measures analyses, including 2 times points (T0–T1 or T0–T2) and only 2 conditions, to find out where the differences in changes over time between the conditions occurred. We included the following covariates in the analyses: age, sex, education, hours at work, employment duration, BMI, walking, and moderate and vigorous-intensity physical activity at baseline. Due to the skewed nature of the outcomes, we did the analyses on square root transformations to improve normality, but for reasons of clarity, we report nontransformed average scores in the tables. We executed this approach using both a retained sample analysis (ie, completer analysis) and an intent-to-treat analysis (last value carried forward). Because we found no differences between the 2 analyses, we report results only of the retained sample analysis.


    Participants’ Characteristics at Baseline and Website Usage

    The total sample (N=213) of employees completing the Web-based questionnaire consisted of 31.5% (67/213) men, 81.7% (174/213) with a high level of education, 91.5% (195/213) who were white collar workers, and 69.5% (148/213) with an employment duration of more than 5 years. Participants had a mean age of 40.3 (SD 9.1) years, worked on average 8.0 (SD 0.7) hours/day, and had a mean BMI of 23.9 (SD 3.4) kg/m2. Table 1 gives an overview of the baseline variables for the 3 intervention groups. The 3 groups did not differ in sociodemographic, work-related, and health-related variables (see Table 1). Self-reported and objectively sitting variables at baseline are presented below. Of those completing the questionnaires, 122/213 (57.3%) employees were willing to wear the activity monitor at baseline. There were no differences between participants who were willing and those who were not willing to wear the activity monitor across all variables (sociodemographic, work-related, health-related, and self-reported sitting time variables; data not shown).

    Table 1. Baseline characteristics for the 3 study groups.
    VariablesTailored group (n=78)Generic group (n=84)Control group (n=51)Group comparisons
    Fdfor χ2dfP value
    Sociodemographic variables

    		Age in years, mean (SD)40.5 (8.6)40.7 (9.7)39.3 (9.0)F2,209=0.44.65

    		Males, n (%)25 (32.1)27 (32.1)15 (29.4)χ22,212=1.9.76

    		High school/university education: n (%)58 (75.3)70 (83.3)46 (90.2)χ22,212=4.8.09
    Work-related variables

    		Hours at work, mean (SD)8.0 (0.9)8.0 (0.6)8.0 (0.6)F2,211=0.36.70

    		White collar occupational status, n (%)74 (96.1)75 (89.3)46 (90.2)χ22,212=2.8.24

    		Employment duration>5 years, n (%)55 (71.4)56 (66.7)37 (72.5)χ22,212=0.7.72
    Health-related variables

    		BMIain kg/m2, mean (SD)24.2 (3.1)23.6 (3.5)23.7 (3.5)F2,211=0.75.48

    		Walking time in minutes/day, mean (SD)18.8 (28.3)21.1 (21.6)18.6 (19.0)F2,208=0.30.74

    		Moderate-intensity PAbin minutes/day, mean (SD)24.7 (26.9)19.3 (20.1)18.0 (19.0)F2,208=1.69.19

    		Vigorous-intensity PA in minutes/day, mean (SD)8.4 (11.5)11.6 (15.6)9.9 (15.6)F2,209=1.05.35

    aBMI: body mass index.

    bPA: physical activity.

    At baseline, all 78 participants in the tailored group completed section 1 (100%). The average time needed to complete the assessment survey was 16.3 minutes. Time spent on the first advice page was on average 20.1 minutes. A total of 66/78 participants completed section 2 (84.6%), 64/78 completed section 3 (82.1%), 60/78 completed section 4 (76.9%), 59/78 completed section 5 (75.6%), and 54/78 completed an action plan (69.2%).

    Intervention Effects on Self-reported Sitting Measures

    Table 2 presents the baseline, 1-month, and 3-month follow-up values of the self-reported sitting for each group. Total workday sitting change from baseline to follow-up was significantly different between the 3 groups (see Table 2). The decrease in sitting time in the tailored group was significantly greater than the decrease in the generic group (P=.002) and the increase in the control group (P=.002). The decrease in the generic group was borderline significantly different from the change in the control group (P=.05). The changes over time in total nonworkday sitting did not differ significantly between the groups (see Table 2).

    Table 2. Mean self-reported sitting at baseline (T0), 1-month follow-up (T1), and 3-month follow-up (T2) for the 3 groups and time × group effects.
    GroupT0T1T2Fdftime×groupP value
    Total sitting in minutes/day, mean (SD)

    		Total workday sitting

    		T0–T1–T2: F4,128=5.65<.001***


    		Tailored (n=36)507 (104)480 (128)425 (110)T0–T1: F2,149=1.45.24


    		Generic (n=64)457 (107)444 (105)437 (95)T0–T2: F2,128=8.47<.001***


    		Control (n=28)449 (126)434 (131)469 (92)


    		Total nonworkday sitting

    		T0–T1–T2: F4,128=1.20.31


    		Tailored (n=36)141 (70)139 (69)132 (70)T0–T1: F2,149=0.63.54


    		Generic (n=64)130 (63)131 (67)141 (77)T0–T2: F2,128=1.15.32


    		Control (n=28)123 (58)117 (47)134 (55)

    Domain-specific sitting in minutes/day, mean (SD)

    		Sitting at worka


    		T0–T1–T2: F4,118=6.72<.001***


    		Tailored (n=33)338 (107)279 (92)259 (88)T0–T1: F2,138=12.5<.001***


    		Generic (n=61)288 (59)279 (64)280 (69)T0–T2: F2,119=10.09<.001***


    		Control (n=24)281 (65)280 (50)288 (48)


    		Sitting during transportb

    		T0–T1–T2: F4,118=0.45.77


    		Tailored (n=33)78 (84)103 (124)58 (49)T0–T1: F2,138=0.47.63


    		Generic (n=61)66 (79)60 (67)48 (31)T0–T2: F2,119=0.01.98


    		Control (n=24)81 (106)74 (88)62 (62)


    		Television viewingb


    		T0–T1–T2: F4,118=1.31.23


    		Tailored (n=33)100 (57)104 (56)106 (61)T0–T1: F2,138=1.24 0.29.29


    		Generic (n=61)95 (62)92 (67)102 (68)T0–T2: F2,119=1.24.29


    		Control (n=24)91 (68)79 (68)82 (61)

    		Personal computer useb

    		T0–T1–T2: F4,118=1.51.20


    		Tailored (n=33)50 (46)53 (47)47 (29)T0–T1: F2,138=0.20.82


    		Generic (n=61)51 (40)52 (44)51 (39)T0–T2: F2,119=1.35.26


    		Control (n=24)58 (62)59 (71)69 (65)


    		Other leisure time sittingb

    		T0–T1–T2: F4,118=1.86.12


    		Tailored (n=33)101 (42)90 (44)75 (32)T0–T1: F2,138=1.68.19


    		Generic (n=61)99 (61)98 (61)97 (46)T0–T2: F2,119=3.64.03*


    		Control (n=24)95 (48)96 (43)102 (64)

    aAverage on workday.

    bAverage of workday and nonworkday.

    * P<.05; *** P<.001.

    Analyses of the domain-specific sitting data showed that changes over time in sitting at work and other leisure time sitting differed significantly between the 3 groups. There was a decrease in sitting at work in the tailored group, which was significantly greater than the changes in the generic group (T0–T1: P<.001, T0–T2: P<.001) and the control group (T0–T1: P=.001, T0–T2: P=.001). The changes over time did not differ significantly between the generic group and the control group (T0–T1: P=.48, T0–T2: P=.26). There was also a decrease in other leisure time sitting from baseline to follow-up in the tailored group, which was significantly greater than the changes over time in the generic group (P=.007) and the control group (P=.02). The changes from baseline to follow-up did not differ significantly between the generic group and the control group (P=.78). The changes over time in sitting during transport, television viewing, and computer use did not differ significantly between the 3 groups (see Table 2).

    Intervention Effects on the Objectively Measured Variables

    Table 3 gives an overview of the sedentary behavior measures derived from the activPAL at baseline, and 1-month and 3-month follow-ups for each group. The changes over time in total sitting while being awake, sitting at work, and standing at work did not differ significantly between the 3 groups (see Table 3). For breaks at work, the only borderline significant difference was found between the tailored group (slight increase in breaks from baseline to follow-up) and the generic group (slight decrease in sitting time from baseline to follow-up, P=.07).

    Table 3. Mean objectively measured variables at baseline (T0), 1-month follow-up (T1), and 3-month follow-up (T2) for the 3 groups and time × group effects.
    GroupT0T1T2Fdftime x groupP value
    Total sitting time awake in hours/day, mean (SD)
    		T0–T1–T2: F4,75=0.56.69

    		Tailored (n=35)576 (109)600 (91)607 (117)T0–T1: F2,80=0.52.60

    		Generic (n=35)578 (101)574 (103)576 (109)T0–T2: F2,79=1.06.35

    		Control (n=23)605 (96)616 (115)623 (100)

    Sitting at work in % work hours, mean (SD)
    		T0–T1–T2: F4,75= F4,75=0.22.93

    		Tailored (n=35)66.8 (15.5)71.7 (14.0)69.0 (13.7)T0–T1: F2,80=0.28.76

    		Generic (n=35)69.0 (13.8)71.2 (15.1)68.8 (15.1)T0–T2: F2,79=0.12.89

    		Control (n=23)74.3 (15.5)78.3 (11.1)74.8 (13.5)

    Standing at work in % work hours, mean (SD)
    		T0–T1–T2: F4,75=0.10.98

    		Tailored (n=35)24.7 (13.5)22.2 (9.0)23.6 (11.7)T0–T1: F2,80=0.05.95

    		Generic (n=35)24.4 (11.3)22.7 (15.4)24.3 (14.4)T0–T2: F2,79=0.11.90

    		Control (n=23)16.3 (9.3)17.1 (7.9)17.8 (9.0)

    Breaks at work in no/work hour, mean (SD)
    		T0–T1–T2: F4,75=2.54.09*

    		Tailored (n=35)3.8 (1.5)3.7 (1.3)4.3 (1.6)T0–T1: F2,80=0.72.40

    		Generic (n=35)3.6 (1.3)3.6 (1.4)3.5 (1.3)T0–T2: F2,79=2.40.11

    		Control (n=23)3.0 (1.4)3.2 (1.4)3.3 (1.6)

    * P<.10


    To our knowledge, this is the first randomized controlled study evaluating 1-month and 3-month follow-up effects of a theory-driven, Web-based, computer-tailored intervention to reduce or interrupt sitting among employees. Results are promising, with positive intervention effects on self-reported sitting time at work, self-reported sitting time during leisure, and objectively measured breaks at work. For these outcomes, the tailored intervention had superior effects to those of the control and the generic condition, confirming our hypothesis. This suggests the significance of computer tailoring in targeting sedentary behavior, as also seen in Web-based advice for other health-related behaviors, such as physical activity and diet [24-26]. However, the expectation that the effect of the generic condition would differ from the control condition was not confirmed. The provision of nontailored Web-based advice seems not sufficient to result in sedentary behavioral change, which is in contrast to behavioral change interventions targeting physical activity or dietary habits, in which generic interventions did have positive effects [48,49].

    It should be noted that the positive findings concerning the decrease in self-reported sitting duration were not reflected in the objective measures, as no effect was found on activPAL-measured total sitting time or sitting time at work. This result emphasizes the importance of combining self-reported and objective measures. The effectiveness study of sit-stand workstations conducted by Chau et al [50] found the opposite pattern, namely positive effects for sitting time at work measured by the activPAL, but no effects for sitting time at work measured with the WSQ. The review of Prince et al [9] found no significant effect differences between self-reported and objectively measured sedentary time. It should be noted that most studies of the review used one of two types of measures: either objective or self-reported measures, but not both. When looking for potential explanations for the discrepancy between our self-reported and objectively measured data, we conducted post hoc correlation analyses (r=.07 for total sitting and r=.11 for work-related sitting), which suggested that the perception of self-reported sitting was different from objectively measured sitting. Some other studies showed that participants underestimated their self-reported sedentary behavior [51]. In contrast, other validation studies of the WSQ, using accelerometers, showed correlates of .34 and more [39]. Based on our study and earlier studies [51], the combination of self-reported and objective measurements is recommended to fully explore findings. A second possible explanation may be that the sample of participants providing the activPAL data were only a subsample (122/213, 57.3% of the total sample at baseline, 105/133, 78.9% at 3-month follow-up). Still, intervention effects on the self-reported measures were not different between employees wearing the monitor and those who did not (data not shown). Even though the subsample is quite large for a field-based study, objective data should ideally have been available for all participants, as the observed statistical power was low to find differences between groups in total sitting and in sitting at work (observed power ranged from .12 to .36) and in standing time at work (observed power=.06).

    Compared with baseline, the self-reported work-related sitting time in the tailored condition was lower at 1-month follow-up (-59 minutes/day) and 3-month follow-up (-79 minutes/day), while this was not the case for the other conditions. These reductions in sitting time are similar to those seen in interventions implementing activity-permissive workstations (-77 minutes/8-hour workday) as shown in the review of Neuhaus et al [21], which included 38 studies. Our reductions in sitting were even higher than those found in a meta-analysis of 34 lifestyle intervention studies (including 8 workplace interventions) having sedentary behavior as an outcome, showing an overall reduction in sedentary time by mean differences of -22 minutes/day in favor of the intervention group [52]. A reduction in sedentary time of just 30 minutes/day is suggested to have clinically meaningful effects on health [9], which indicates that our computer-tailored intervention may potentially be useful in public health promotion. However, in the review of Martin et al [53], the authors concluded that it is not known whether the effective interventions aimed at reducing sedentary behavior resulted in clinically meaningful and sustained improvements in health outcomes, as it was not possible to determine the intervention effect of reduced sedentary behavior on cardiometabolic risk, body composition, and mental health outcomes. Still, in a Spanish Internet-delivered workplace intervention focusing on decreasing occupational sitting (via goal setting for step counts and walking), occupational sitting time (-22 minutes/day) and waist circumference (-0.8 cm) decreased in the intervention group [54].

    In our subsample wearing the activPAL, we found a positive intervention effect at follow-up for breaks during work (+0.4 breaks/work hour, ~3.2 breaks in an 8-hour workday, an increase from 30 to 34 breaks in an 8-hour workday) in the tailored condition compared with no change in the generic condition. In the review of Martin et al [53], pooled intervention effects on sedentary behavior patterns indicated no statistically significant effect for the number of sitting breaks per hour. The clinical meaning of the effect we observed is, however, unknown, as the dose-response relation regarding breaks is unclear [52]. Still, an eHealth intervention to reduce prolonged occupational sitting that passively prompted desk-based employees every 45 minutes to stand and perform nonexercise physical activity did examine the clinical effects. The study resulted in activity breaks about 6 times/workday for about 1.3 minutes at a time in the experimental group and showed that the mean arterial pressure significantly decreased [55] and the work-related energy expenditure increased [56] in the experimental group compared with a control group. Given that we found an increase in breaks in our study, we can assume that this computer-tailored intervention can also result in significant health effects; however, we did not track the duration of the activity breaks.

    It may be surprising that an individual-based intervention such as our computer-tailored intervention resulted in such a relatively high reduction in self-reported sitting time at work. In the case of implementing sit-stand workstations, it is reasonable that sitting time is substantially reduced, as the environment is changed to do so, but without standing desks one could expect the intervention to have less effect on total sitting duration and more on the sitting pattern. Based on the feasibility and acceptability study of our computer-tailored intervention, pointing out that employees perceived interrupting sitting to be more achievable than reducing workplace sitting, this could also be expected to be the case here [30]. Nevertheless, our intervention seemed to affect both the pattern (objectively measured data) and the duration (self-reported data) of sitting.

    We found no other 1-month follow-up effects on self-reported outcomes (sitting during transport, television viewing, computer use, leisure time sitting) or other objectively measured outcomes (total sitting time, sitting and standing time at work). However, we did find significant and positive 3-month follow-up intervention effects for self-reported total workday sitting and self-reported leisure time sitting. The change over time was more positive in the tailored condition than in the other conditions. The fact that leisure time sitting decreased (-26 minutes/day) from baseline to follow-up was surprising, as the advice mostly focused on work-related aspects: work hours, commuting, and (lunch) breaks. Still, this may mean that employees transferred the information and tips regarding one specific setting (work) to another (leisure). The study of Chau et al [50] obtained a similar result, showing that self-reported television viewing time decreased after a workplace intervention in which employees used a sit-stand workstation for 4 weeks. The authors argued that a reduction in television viewing time would be a welcome side effect of their intervention, especially because compensatory effects for occupational sitting (ie, less sitting at work would lead to more sitting at home) were not found in other previous studies [57-59]. In our study, however, we found no effect on television viewing.

    Study Strengths and Limitations

    Our study has several strengths and limitations to take into account. The first strength is the randomized controlled design with a large sample of employees relative to other workplace interventions focusing on sedentary behavior. Second, the use of the activPAL as an objective measure for the outcomes was a strength, as self-reported measures can have recall and social desirability biases. However, as stated earlier, the first limitation is that we used this monitor only in a subsample of employees willing to wear the monitor, which is probably a result of the field-based approach of this study. Further, from a methodological point of view, it would have been more suitable to randomly allocate the monitors within the total sample in order to avoid sampling bias. However, from a compliance point of view, we believed it was better to provide a monitor only to those willing to wear one, in order to limit dropout. The dropout rate was lower (17/122, 13.9%) in the group wearing a monitor (and completing the questionnaires) than in the sample only completing the questionnaires (80/213, 37.6%). A study on the retention rates in physical activity interventions in workplace, health care, and home- or community-based settings revealed a mean retention rate of 78%, with minimal differences between intervention settings [60]. In our study, the mean retention rate was 74.3% (only questionnaire: 133/213, 62.4%; questionnaire and monitor: 105/122, 86.1%). The second limitation, probably resulting from the field-based approach, is the relatively low initial response rate (230/1061, 21.5%), which is comparable with another workplace intervention study using only 1 mailing to recruit (response rate 20%) [61]. The study of Waters et al [60] showed that response rates in physical activity interventions in adults range from 20% to 89%. Third, we recruited participants in only 2 companies, with worksites in 3 different settings, probably resulting in different workplace cultures. In addition, the study sample consisted of mainly healthy weight, highly educated women. This is in line with other workplace physical activity interventions in which participants were found to be younger, more educated, and healthier than nonparticipants [60]. All these factors may compromise generalizability of the results. Fourth, we do not know the long-term effects of this intervention, as we completed the follow-up measures only 3 months after baseline. Martin et al [53] found that interventions of up to 3 months resulted in a significant reduction in sedentary time (-48 minutes/day) in favor of the intervention group, whereas longer intervention durations of more than 3 months did not show beneficial intervention effects.

    This study opens perspectives for future research. The effect of this intervention on psychosocial correlates should be tested, including the mediating effect of the change in these factors on the behavioral effects. As it stands, we do not know what the active intervention components are. Further, future research should investigate whether this tailored intervention would be more effective in combination with other (environmental) strategies, for example the use of sit-stand desks. Previous interventions also chose multicomponent programs to tackle the problems of too much sitting [50]. Therefore, this intervention could be an additional component in studies based on ecological models, intervening simultaneously at multiple levels.

    Conclusions

    To our knowledge, this is the first intervention study to describe the effectiveness of a theory-driven, Web-based, interactive computer-tailored intervention aimed at reducing and interrupting sitting at work. The computer-tailored approach showed promising outcomes to address sitting time, as the tailored intervention was successful in decreasing self-reported sitting time at work and during leisure time, and in increasing objectively measured breaks at work compared with the generic and control conditions, which had no significant impact. This suggests that this computer-tailored intervention might have potential to contribute to the health promotion field.

    Authors' Contributions

    KDC conceived the study, participated in its design and coordination, analyzed the data, and drafted the manuscript. IDB, GC, and CV conceived the study, participated in its design, and assisted in drafting the manuscript. All authors read, revised, and approved the final manuscript.

    KDC is supported by the Research Foundation Flanders (FWO) (postdoctoral research fellowship: FWO11/PDO/097).

    Conflicts of Interest

    None declared. The authors are the developers of the intervention.

    ‎

    Multimedia Appendix 1

    Screenshots of the start to stand tool.

    PDF File (Adobe PDF File), 866KB
    ‎

    Multimedia Appendix 2

    CONSORT-EHEALTH (V 1.6.1) checklist.

    PDF File (Adobe PDF File), 11MB
    1. Sedentary Behaviour Research Network. Letter to the editor: standardized use of the terms "sedentary" and "sedentary behaviours". Appl Physiol Nutr Metab 2012 Jun;37(3):540-542. [CrossRef] [Medline]
    2. Thorp AA, Healy GN, Winkler E, Clark BK, Gardiner PA, Owen N, et al. Prolonged sedentary time and physical activity in workplace and non-work contexts: a cross-sectional study of office, customer service and call centre employees. Int J Behav Nutr Phys Act 2012;9:128 [FREE Full text] [CrossRef] [Medline]
    3. Van Acker R, De Meester F. Langdurig zitten: dé uitdaging van de 21ste eeuw: syntheserapport als actuele onderbouw voor de factsheet sedentair gedrag. Brussels: Vlaams Instituut voor Gezondheidspromotie en Ziektepreventie; 2015:1-80.
    4. Vandelanotte C, Duncan MJ, Short C, Rockloff M, Ronan K, Happell B, et al. Associations between occupational indicators and total, work-based and leisure-time sitting: a cross-sectional study. BMC Public Health 2013;13:1110 [FREE Full text] [CrossRef] [Medline]
    5. Thorp AA, Owen N, Neuhaus M, Dunstan DW. Sedentary behaviors and subsequent health outcomes in adults a systematic review of longitudinal studies, 1996-2011. Am J Prev Med 2011 Aug;41(2):207-215. [CrossRef] [Medline]
    6. Proper KI, Singh AS, van Mechelen W, Chinapaw M. Sedentary behaviors and health outcomes among adults: a systematic review of prospective studies. Am J Prev Med 2011 Feb;40(2):174-182. [CrossRef] [Medline]
    7. Healy GN, Wijndaele K, Dunstan DW, Shaw JE, Salmon J, Zimmet PZ, et al. Objectively measured sedentary time, physical activity, and metabolic risk: the Australian Diabetes, Obesity and Lifestyle Study (AusDiab). Diabetes Care 2008 Feb;31(2):369-371. [CrossRef] [Medline]
    8. van Uffelen J, Wong J, Chau JY, van der Ploeg H, Riphagen I, Gilson ND, et al. Occupational sitting and health risks: a systematic review. Am J Prev Med 2010 Oct;39(4):379-388. [CrossRef] [Medline]
    9. Prince SA, Saunders TJ, Gresty K, Reid RD. A comparison of the effectiveness of physical activity and sedentary behaviour interventions in reducing sedentary time in adults: a systematic review and meta-analysis of controlled trials. Obes Rev 2014 Nov;15(11):905-919 [FREE Full text] [CrossRef] [Medline]
    10. Shrestha N, Ijaz S, Kukkonen-Harjula K, Kumar S, Nwankwo C. Workplace interventions for reducing sitting at work. Cochrane Database Syst Rev  2015;1:1-132. [CrossRef] [Medline]
    11. Tew GA, Posso MC, Arundel CE, McDaid CM. Systematic review: height-adjustable workstations to reduce sedentary behaviour in office-based workers. Occup Med (Lond) 2015 Jul;65(5):357-366. [CrossRef] [Medline]
    12. Verweij LM, Proper K, Weel A, Hulshof C, van Mechelen W. The application of an occupational health guideline reduces sedentary behaviourincreases fruit intake at work: results from an RCT. Occup Environ Med 2012;69(7):500-507. [CrossRef] [Medline]
    13. Stephens SK, Winkler EA, Trost SG, Dunstan DW, Eakin EG, Chastin SF, et al. Intervening to reduce workplace sitting time: how and when do changes to sitting time occur? Br J Sports Med 2014 Jul;48(13):1037-1042. [CrossRef] [Medline]
    14. Neuhaus M, Healy G, Dunstan D, Owen N, Eakin E. Workplace sitting and height-adjustable workstations: A randomized controlled trial. Am J Prev Med 2014;46(1):30-40. [CrossRef] [Medline]
    15. Alkhajah TA, Reeves MM, Eakin EG, Winkler EA, Owen N, Healy GN. Sit-stand workstations: a pilot intervention to reduce office sitting time. Am J Prev Med 2012 Sep;43(3):298-303. [CrossRef] [Medline]
    16. Pronk NP, Katz AS, Lowry M, Payfer JR. Reducing occupational sitting time and improving worker health: the Take-a-Stand Project, 2011. Prev Chronic Dis 2012;9:E154 [FREE Full text] [Medline]
    17. Gilson ND, Suppini A, Ryde GC, Brown HE, Brown WJ. Does the use of standing 'hot' desks change sedentary work time in an open plan office? Prev Med 2012 Jan;54(1):65-67. [CrossRef] [Medline]
    18. Carr LJ, Karvinen K, Peavler M, Smith R, Cangelosi K. Multicomponent intervention to reduce daily sedentary time: a randomised controlled trial. BMJ Open 2013;3(10):e003261 [FREE Full text] [CrossRef] [Medline]
    19. Evans RE, Fawole HO, Sheriff SA, Dall PM, Grant PM, Ryan CG. Point-of-choice prompts to reduce sitting time at work: a randomized trial. Am J Prev Med 2012 Sep;43(3):293-297. [CrossRef] [Medline]
    20. Smith L, Pedersen S. The effect of education on compliance to a workplace health and wellbeing intervention: closing the loop. Universal J Public Health 2013;1(3):97-102.
    21. Neuhaus M, Eakin EG, Straker L, Owen N, Dunstan DW, Reid N, et al. Reducing occupational sedentary time: a systematic review and meta-analysis of evidence on activity-permissive workstations. Obes Rev 2014 Oct;15(10):822-838. [CrossRef] [Medline]
    22. De Cocker K, Veldeman C, De Bacquer D, Braeckman L, Owen N, Cardon G, et al. Acceptability and feasibility of potential intervention strategies for influencing sedentary time at work: focus group interviews in executives and employees. Int J Behav Nutr Phys Act Feb 18 2015:12. [CrossRef] [Medline]
    23. Gardner B, Smith L, Lorencatto F, Hamer M, Biddle SJ. How to reduce sitting time? A review of behaviour change strategies used in sedentary behaviour reduction interventions among adults. Health Psychol Rev 2015 Sep 16:1-24. [CrossRef] [Medline]
    24. Neville LM, Milat AJ, O'Hara B. Computer-tailored weight reduction interventions targeting adults: a narrative systematic review. Health Promot J Austr 2009 Apr;20(1):48-57. [Medline]
    25. Kroeze W, Werkman A, Brug J. A systematic review of randomized trials on the effectiveness of computer-tailored education on physical activity and dietary behaviors. Ann Behav Med 2006 Jun;31(3):205-223. [CrossRef] [Medline]
    26. Lustria ML, Cortese J, Noar SM, Glueckauf RL. Computer-tailored health interventions delivered over the Web: review and analysis of key components. Patient Educ Couns 2009 Feb;74(2):156-173. [CrossRef] [Medline]
    27. Internet World Stats: Usage and Population Statistics. Bogota, Columbia: Miniwatts Marketing Group; 2014 Nov 30. World Internet Usage and Population Statistics June 30, 2014 - Mid-Year Update   URL: http://www.internetworldstats.com/stats.htm [accessed 2015-01-28] [WebCite Cache]
    28. Broekhuizen K, Kroeze W, van Poppel MN, Oenema A, Brug J. A systematicreviewof randomized controlled trials on the effectiveness of computer-tailored physical activity and dietary behavior promotion programs: an update. Ann Behav Med 2012;44(2):259-286. [CrossRef] [Medline]
    29. Kelders SM, Kok RN, Ossebaard HC, Van Gemert-Pijnen J. Persuasive system design does matter: a systematic review of adherence to web-based interventions. J Med Internet Res 2012;14(6):e152 [FREE Full text] [CrossRef] [Medline]
    30. De Cocker K, De Bourdeaudhuij I, Cardon G, Vandelanotte C. Theory-driven, web-based, computer-tailored advice to reduce and interrupt sitting at work: development, feasibility and acceptability testing among employees. BMC Public Health 2015;15(1):959 [FREE Full text] [CrossRef] [Medline]
    31. Swartz A,  Rote A, Welch W, Maeda H, Hart T, Cho Y, et al. Prompts to disrupt sitting time and increase physical activity at work, 2011-2012. Prev Chronic Dis 2014;11:E73. [CrossRef] [Medline]
    32. Deci E, Ryan R. Handbook of Self-determination Research. Rochester, NY: University of Rochester Press; 2002.
    33. Ajzen I. The theory of planned behavior. Organ Behav Hum 1991;50(2):179-211.
    34. Maes S, Karoly P. Self-regulation assessment and intervention in physical health and illness: a review. Applied Psychol: Int Rev 2005;54(2):267-299.
    35. Vandelanotte C, Spathonis KM, Eakin EG, Owen N. Website-delivered physical activity interventions a review of the literature. Am J Prev Med 2007 Jul;33(1):54-64. [CrossRef] [Medline]
    36. Noar SM, Benac CN, Harris MS. Does tailoring matter? Meta-analytic review of tailored print health behavior change interventions. Psychol Bull 2007 Jul;133(4):673-693. [CrossRef] [Medline]
    37. Rutten GM, Savelberg HH, Biddle SJ, Kremers SP. Interrupting long periods of sitting: good STUFF. Int J Behav Nutr Phys Act 2013;10:1 [FREE Full text] [CrossRef] [Medline]
    38. Gollwitzer P. Implementation intentions: strong effects of simple plans. Am Psychol 1999;54:493-503.
    39. Chau JY, van der Ploeg HP, Dunn S, Kurko J, Bauman AE. A tool for measuring workers' sitting time by domain: the Workforce Sitting Questionnaire. Br J Sports Med 2011 Dec;45(15):1216-1222. [CrossRef] [Medline]
    40. Clark BK, Thorp AA, Winkler E, Gardiner PA, Healy GN, Owen N, et al. Validity of self-reported measures of workplace sitting time and breaks in sitting time. Med Sci Sports Exerc 2011 Oct;43(10):1907-1912. [CrossRef] [Medline]
    41. Craig CL, Marshall AL, Sjöström M, Bauman AE, Booth ML, Ainsworth BE, et al. International physical activity questionnaire: 12-country reliability and validity. Med Sci Sports Exerc 2003 Aug;35(8):1381-1395. [CrossRef] [Medline]
    42. Vandelanotte C, De Bourdeaudhuij I, Sallis J, Philippaerts R, Sjöström M. Reliability and validity of a computerised and Dutch version of the International Physical Activity Questionnaire (IPAQ). J Phys Act Health 2005;2:63-75.
    43. Kozey-Keadle S, Libertine A, Lyden K, Staudenmayer J, Freedson PS. Validation of wearable monitors for assessing sedentary behavior. Med Sci Sports Exerc 2011 Aug;43(8):1561-1567. [CrossRef] [Medline]
    44. Chastin SF, Granat MH. Methods for objective measure, quantification and analysis of sedentary behaviour and inactivity. Gait Posture 2010 Jan;31(1):82-86. [CrossRef] [Medline]
    45. Crutzen R, Roosjen JL, Poelman J. Using Google Analytics as a process evaluation method for Internet-delivered interventions: an example on sexual health. Health Promot Int 2013 Mar;28(1):36-42 [FREE Full text] [CrossRef] [Medline]
    46. Guidelines for Data Processing and Analysis of the International Physical Activity Questionnaire (IPAQ)—Short and Long Forms. 2005 Nov.   URL: https:/​/docs.​google.com/​viewer?a=v&pid=sites&srcid=ZGVmYXVsdGRvbWFpbnx0aGVpcGFxfGd4OjE0NDgxMDk3NDU1YWRlZTM [accessed 2016-04-19] [WebCite Cache]
    47. Cerin E. Statistical approaches to testing the relationships of the built environment with resident-level physical activity behaviorhealth outcomes in cross-sectional studies with cluster sampling. J Plann Lit 2010 Dec 15:151-167. [CrossRef]
    48. Spittaels H, De Bourdeaudhuij I, Vandelanotte C. Evaluation of a website-delivered computer-tailored intervention for increasing physical activity in the general population. Prev Med 2007 Mar;44(3):209-217. [CrossRef] [Medline]
    49. De Bourdeaudhuij I, Stevens V, Vandelanotte C, Brug J. Evaluation of an interactive computer-tailored nutrition intervention in a real-life setting. Ann Behav Med 2007 Feb;33(1):39-48. [CrossRef] [Medline]
    50. Chau JY, Daley M, Dunn S, Srinivasan A, Do A, Bauman A, van der Ploeg HP. The effectiveness of sit-stand workstations for changing office workers' sitting time: results from the Stand@Work randomized controlled trial pilot. Int J Behav Nutr Phys Act 2014:127. [CrossRef] [Medline]
    51. Matton L, Wijndaele K, Duvigneaud N, Duquet W, Philippaerts R, Thomis M, et al. Reliability and validity of the Flemish Physical Activity Computerized Questionnaire in adults. Res Q Exerc Sport 2007 Sep;78(4):293-306. [CrossRef] [Medline]
    52. Carson V, Wong SL, Winkler E, Healy GN, Colley RC, Tremblay MS. Patterns of sedentary time and cardiometabolic risk among Canadian adults. Prev Med 2014 Aug;65:23-27. [CrossRef] [Medline]
    53. Martin A, Fitzsimons C, Jepson R, Saunders DH, van der Ploeg HP, Teixeira PJ, EuroFIT Consortium. Interventions with potential to reduce sedentary time in adults: systematic review and meta-analysis. Br J Sports Med 2015 Aug;49(16):1056-1063. [CrossRef] [Medline]
    54. Puig-Ribera A, Bort-Roig J, González-Suárez AM, Martínez-Lemos I, Giné-Garriga M, Fortuño J, et al. Patterns of impact resulting from a 'sit less, move more' web-based program in sedentary office employees. PLoS One 2015;10(4):e0122474 [FREE Full text] [CrossRef] [Medline]
    55. Mainsbridge CP, Cooley PD, Fraser SP, Pedersen SJ. The effect of an e-health intervention designed to reduce prolonged occupational sitting on mean arterial pressure. J Occup Environ Med 2014 Nov;56(11):1189-1194 [FREE Full text] [CrossRef] [Medline]
    56. Pedersen SJ, Cooley PD, Mainsbridge C. An e-health intervention designed to increase workday energy expenditure by reducing prolonged occupational sitting habits. Work 2014;49(2):289-295. [CrossRef] [Medline]
    57. Chau JY, van der Ploeg HP, Merom D, Chey T, Bauman AE. Cross-sectional associations between occupational and leisure-time sitting, physical activity and obesity in working adults. Prev Med 2012;54(3-4):195-200. [CrossRef] [Medline]
    58. Jans MP, Proper KI, Hildebrandt VH. Sedentary behavior in Dutch workers: differences between occupations and business sectors. Am J Prev Med 2007 Dec;33(6):450-454. [CrossRef] [Medline]
    59. Tigbe WW, Lean MEJ, Granat MH. A physically active occupation does not result in compensatory inactivity during out-of-work hours. Prev Med 2011;53(1-2):48-52. [CrossRef] [Medline]
    60. Waters LA, Galichet B, Owen N, Eakin E. Who participates in physical activity intervention trials? J Phys Act Health 2011 Jan;8(1):85-103. [Medline]
    61. Wang PS, Beck AL, McKenas DK, Meneades LM, Pronk NP, Saylor JS, et al. Effects of efforts to increase response rates on a workplace chronic condition screening survey. Med Care 2002 Sep;40(9):752-760. [CrossRef] [Medline]

    ‎
    BMI: body mass index
    IPAQ: International Physical Activity Questionnaire
    SMART: specific, measurable, attainable, relevant, and time-bound
    T0: baseline
    T1: 1-month follow-up
    T2: 3-month follow-up
    WSQ: Workforce Sitting Questionnaire

    Edited by A Moorhead; submitted 22.10.15; peer-reviewed by J Torous, S Pedersen; comments to author 27.11.15; revised version received 12.01.16; accepted 21.02.16; published 31.05.16

    Copyright

    ©Katrien De Cocker, Ilse De Bourdeaudhuij, Greet Cardon, Corneel Vandelanotte. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 31.05.2016.

    This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research, is properly cited. The complete bibliographic information, a link to the original publication on http://www.jmir.org/, as well as this copyright and license information must be included.